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BDBM123171 US8742110, 1-20

SMILES: OC(=O)c1ccc(cc1)N1CC2(CCN(Cc3cn(nc3-c3ccc(F)cc3)-c3ccc(F)cc3)CC2)OC1=O

InChI Key: InChIKey=FPEAOHVIXSTOGM-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 123171   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM123171
PNG
(US8742110, 1-20)
Show SMILES OC(=O)c1ccc(cc1)N1CC2(CCN(Cc3cn(nc3-c3ccc(F)cc3)-c3ccc(F)cc3)CC2)OC1=O
Show InChI InChI=1S/C30H26F2N4O4/c31-23-5-1-20(2-6-23)27-22(18-36(33-27)26-11-7-24(32)8-12-26)17-34-15-13-30(14-16-34)19-35(29(39)40-30)25-9-3-21(4-10-25)28(37)38/h1-12,18H,13-17,19H2,(H,37,38)
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PC sid
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Similars

US Patent
n/an/a 5.33n/an/an/an/a7.8n/a



Merck Sharp & Dohme Corp.

US Patent


Assay Description
SSTR5 binding assays can be performed by labeling somatostatin and determining the ability of a compound to inhibit somatostatin binding. (Poitout et...


US Patent US8742110 (2014)


BindingDB Entry DOI: 10.7270/Q26H4G39
More data for this
Ligand-Target Pair