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BDBM123418 US8741944, 39

SMILES: NS(=O)(=O)c1ccc(cc1)-n1nc(cc1-c1ccc(CCN=[N+]=[N-])cc1)C(F)(F)F

InChI Key: InChIKey=DZZQBBYGNCJQAK-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 123418   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
3-phosphoinositide dependent protein kinase-1


(Homo sapiens (Human))
BDBM123418
PNG
(US8741944, 39)
Show SMILES NS(=O)(=O)c1ccc(cc1)-n1nc(cc1-c1ccc(CCN=[N+]=[N-])cc1)C(F)(F)F
Show InChI InChI=1S/C18H15F3N6O2S/c19-18(20,21)17-11-16(13-3-1-12(2-4-13)9-10-24-26-22)27(25-17)14-5-7-15(8-6-14)30(23,28)29/h1-8,11H,9-10H2,(H2,23,28,29)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 3.20E+4n/an/an/an/an/an/a



The Ohio State University Research Foundation

US Patent


Assay Description
PDK-1 kinase activity This in vitro assay was performed using a PDK-1 kinase assay kit (Upstate, Lake Placid, N.Y.) according to the vendor's ins...


US Patent US8741944 (2014)


BindingDB Entry DOI: 10.7270/Q2TB15M1
More data for this
Ligand-Target Pair