BDBM123462 US8741923, 35

SMILES COCc1cc(ccc1-c1ccccc1C)-c1nc(no1)-c1ccc2CCN(CCC(O)=O)Cc2c1

InChI Key InChIKey=DEWYUPBJICTOGK-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 123462   

TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Merck Serono

US Patent
LigandPNGBDBM123462(US8741923, 35)
Affinity DataKi:  0.230nM ΔG°:  -12.2kcal/molepH: 7.4 T: 2°CAssay Description:Receptor binding assay: Membranes were prepared from CHO cells expressing S1P1 or S1P3 for use in ligand and 35S-GTPγS binding studies. Cells we...More data for this Ligand-Target Pair
In DepthDetails US Patent