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BDBM123598 US8748624, 97

SMILES: OC(=O)CCNC(=O)c1ccc(cn1)-c1cc(F)c(F)cc1C(=O)Nc1ccc(cc1)-c1ccc(Cl)cc1

InChI Key: InChIKey=JCHQBTREKQYBAP-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 123598   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glucagon receptor


(Homo sapiens (Human))
BDBM123598
PNG
(US8748624, 97)
Show SMILES OC(=O)CCNC(=O)c1ccc(cn1)-c1cc(F)c(F)cc1C(=O)Nc1ccc(cc1)-c1ccc(Cl)cc1
Show InChI InChI=1S/C28H20ClF2N3O4/c29-19-6-1-16(2-7-19)17-3-8-20(9-4-17)34-27(37)22-14-24(31)23(30)13-21(22)18-5-10-25(33-15-18)28(38)32-12-11-26(35)36/h1-10,13-15H,11-12H2,(H,32,38)(H,34,37)(H,35,36)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
57.4n/an/an/an/an/an/a7.4n/a



Janssen Pharmaceutica NV

US Patent


Assay Description
The binding assay was performed by a filtration method in a 384 well format. Membranes at a final protein concentration of 6 μg/well were incuba...


US Patent US8748624 (2014)


BindingDB Entry DOI: 10.7270/Q29885QP
More data for this
Ligand-Target Pair