BDBM123780 2-{[3-(aminomethyl)-2-(2-methylpropyl)-1-oxo-4- phenylisoquinolin-6-yl]oxy}acetamide (19)::CHEMBL1808475
SMILES CC(C)Cn1c(CN)c(-c2ccccc2)c2cc(OCC(N)=O)ccc2c1=O
InChI Key InChIKey=GODOFGUHKFCHSR-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 123780
Affinity DataIC50: 240nMAssay Description:The HypoGen module in DS2.5 was employed to produce pharmaphores with the training set compounds.More data for this Ligand-Target Pair
Affinity DataIC50: 47nMAssay Description:Inhibition of human Dipeptidyl peptidase-4 expressed in Caco-2 cells using Gly-Pro-pNA.Tos as substrate after 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of bovine spleen capthepsin CMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibition of DPP4 in rat plasma incubated for 60 mins using H-lys-Ala-pNA.2HCl substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 6.10E+4nMAssay Description:Inhibition of DPP4 in rat spleen incubated for 60 mins using H-lys-Ala-pNA.2HCl substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 240nMAssay Description:Inhibition of human DPP4 isolated from from human CaCo2 cells incubated for 15 mins using Gly-Pro-pNA.Tos substrateMore data for this Ligand-Target Pair