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BDBM124044 US8754233, 4-Benzothiazol-2-yl-N3-(3-dimethylamino-propyl)-1H-pyrazole-3,5-diamine

SMILES: CN(C)CCCNc1[nH]nc(N)c1-c1nc2ccccc2s1

InChI Key: InChIKey=JDXRQOFYLUYCEK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 124044   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serine/threonine-protein kinase ILK-1


(Homo sapiens (Human))
BDBM124044
PNG
(US8754233, 4-Benzothiazol-2-yl-N3-(3-dimethylamino...)
Show SMILES CN(C)CCCNc1[nH]nc(N)c1-c1nc2ccccc2s1
Show InChI InChI=1S/C15H20N6S/c1-21(2)9-5-8-17-14-12(13(16)19-20-14)15-18-10-6-3-4-7-11(10)22-15/h3-4,6-7H,5,8-9H2,1-2H3,(H4,16,17,19,20)
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Similars

US Patent
n/an/a 300n/an/an/an/an/a40



Dermira (Canada), Inc.

US Patent


Assay Description
5 uL of each compound dilution were robotically pipetted to Costar serocluster plates maintaining the same plate layout. All assay mixtures consisted...


US Patent US8754233 (2014)


BindingDB Entry DOI: 10.7270/Q23N2231
More data for this
Ligand-Target Pair