BDBM124059 US8754233, 5-Methyl-4-(6-pyrrolidin-1-ylmethyl-benzothiazol-2-yl)-2H-pyrazol-3-ylamine

SMILES: Cc1[nH]nc(N)c1-c1nc2ccc(CN3CCCC3)cc2s1

InChI Key: InChIKey=HUKMBIBKVQGNFM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 124059   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase ILK-1 (Homo sapiens (Human))	BDBM124059 (US8754233, 5-Methyl-4-(6-pyrrolidin-1-ylmethyl-ben...) Show SMILES Cc1[nH]nc(N)c1-c1nc2ccc(CN3CCCC3)cc2s1 Show InChI InChI=1S/C16H19N5S/c1-10-14(15(17)20-19-10)16-18-12-5-4-11(8-13(12)22-16)9-21-6-2-3-7-21/h4-5,8H,2-3,6-7,9H2,1H3,(H3,17,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	40
Dermira (Canada), Inc. US Patent					Assay Description 5 uL of each compound dilution were robotically pipetted to Costar serocluster plates maintaining the same plate layout. All assay mixtures consisted...				US Patent US8754233 (2014) BindingDB Entry DOI: 10.7270/Q23N2231
					More data for this Ligand-Target Pair