BDBM12414 CHEMBL27601::benzenesulfonamide::hCA inhibitor, 6

SMILES: c1ccc(cc1)S(=O)(=O)N

InChI Key: InChIKey=KHBQMWCZKVMBLN-UHFFFAOYSA-N

Data: 14 KI  2 IC50  10 Kd

PDB links: 9 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 26 hits for monomerid = 12414   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 2 (Human)	BDBM12414 (CHEMBL27601 | benzenesulfonamide | hCA inhibitor, ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	660	n/a	n/a	n/a	7.0	25
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Platelet-activating factor acetylhydrolase (Human)	BDBM12414 (CHEMBL27601 | benzenesulfonamide | hCA inhibitor, ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-activating factor acetylhydrolase (Human)	BDBM12414 (CHEMBL27601 | benzenesulfonamide | hCA inhibitor, ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	3.40E+6	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 2 (Human)	BDBM12414 (CHEMBL27601 | benzenesulfonamide | hCA inhibitor, ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.14E+6	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 2 (Human)	BDBM12414 (CHEMBL27601 | benzenesulfonamide | hCA inhibitor, ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.15E+6	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 1 (Human)	BDBM12414 (CHEMBL27601 | benzenesulfonamide | hCA inhibitor, ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	7.14E+3	n/a	n/a	n/a	7.0	n/a
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Carbonic anhydrase 2 (Human)	BDBM12414 (CHEMBL27601 | benzenesulfonamide | hCA inhibitor, ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.79E+3	n/a	n/a	n/a	7.0	n/a
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Carbonic anhydrase 7 (Human)	BDBM12414 (CHEMBL27601 | benzenesulfonamide | hCA inhibitor, ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	6.67E+3	n/a	n/a	n/a	7.0	n/a
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Carbonic anhydrase 12 (Human)	BDBM12414 (CHEMBL27601 | benzenesulfonamide | hCA inhibitor, ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.25E+4	n/a	n/a	n/a	7.0	n/a
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Carbonic anhydrase 13 (Human)	BDBM12414 (CHEMBL27601 | benzenesulfonamide | hCA inhibitor, ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.00E+4	n/a	n/a	n/a	7.0	n/a
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Carbonic anhydrase 1/2/5B, mitochondrial (Human)	BDBM12414 (CHEMBL27601 | benzenesulfonamide | hCA inhibitor, ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 1 (Human)	BDBM12414 (CHEMBL27601 | benzenesulfonamide | hCA inhibitor, ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	4.03E+3	n/a	n/a	n/a	7.0	25
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Carbonic anhydrase 2 (Bovine)	BDBM12414 (CHEMBL27601 | benzenesulfonamide | hCA inhibitor, ...) Show SMILES Show InChI	GoogleScholar	UniChem		178	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 2 (Bovine)	BDBM12414 (CHEMBL27601 | benzenesulfonamide | hCA inhibitor, ...) Show SMILES Show InChI	GoogleScholar	UniChem		178	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 2 (Human)	BDBM12414 (CHEMBL27601 | benzenesulfonamide | hCA inhibitor, ...) Show SMILES Show InChI	GoogleScholar	UniChem		305	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 2 (Human)	BDBM12414 (CHEMBL27601 | benzenesulfonamide | hCA inhibitor, ...) Show SMILES Show InChI	GoogleScholar	UniChem		430	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 2 (Human)	BDBM12414 (CHEMBL27601 | benzenesulfonamide | hCA inhibitor, ...) Show SMILES Show InChI	GoogleScholar	UniChem		1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 2 (Human)	BDBM12414 (CHEMBL27601 | benzenesulfonamide | hCA inhibitor, ...) Show SMILES Show InChI	GoogleScholar	UniChem		1.10E+3	-8.12	n/a	n/a	n/a	n/a	n/a	7.4	25
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Carbonic anhydrase 4 (Human)	BDBM12414 (CHEMBL27601 | benzenesulfonamide | hCA inhibitor, ...) Show SMILES Show InChI	GoogleScholar	UniChem		1.12E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 6 (Human)	BDBM12414 (CHEMBL27601 | benzenesulfonamide | hCA inhibitor, ...) Show SMILES Show InChI	GoogleScholar	UniChem		2.97E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 1 (Human)	BDBM12414 (CHEMBL27601 | benzenesulfonamide | hCA inhibitor, ...) Show SMILES Show InChI	GoogleScholar	UniChem		3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 6 (Human)	BDBM12414 (CHEMBL27601 | benzenesulfonamide | hCA inhibitor, ...) Show SMILES Show InChI	GoogleScholar	UniChem		4.11E+3	-7.34	n/a	n/a	n/a	n/a	n/a	7.4	25
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Carbonic anhydrase 2 (Human)	BDBM12414 (CHEMBL27601 | benzenesulfonamide | hCA inhibitor, ...) Show SMILES Show InChI	GoogleScholar	UniChem		5.87E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 1 (Human)	BDBM12414 (CHEMBL27601 | benzenesulfonamide | hCA inhibitor, ...) Show SMILES Show InChI	GoogleScholar	UniChem		1.24E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 1 (Human)	BDBM12414 (CHEMBL27601 | benzenesulfonamide | hCA inhibitor, ...) Show SMILES Show InChI	GoogleScholar	UniChem		4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 1 (Human)	BDBM12414 (CHEMBL27601 | benzenesulfonamide | hCA inhibitor, ...) Show SMILES Show InChI	GoogleScholar	UniChem		4.00E+4	-6.00	n/a	n/a	n/a	n/a	n/a	7.4	25
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