BDBM124144 US8754075, 14
SMILES C[C@@]1(N=C(N)OC[C@@H]1F)c1cc(NC(=O)c2ccc(cn2)C#CC2CC2)ccc1F
InChI Key InChIKey=JIXCAGUAYBCKGM-SIKLNZKXSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 124144
Affinity DataIC50: 9nMT: 2°CAssay Description:The assay uses the principle of inhibition of human TMEM27 cleavage by endogenous cellular BACE2 in the Ins1e rat cell line and shedding from the cel...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMT: 2°CAssay Description:The assay uses the principle of inhibition of human TMEM27 cleavage by endogenous cellular BACE2 in the Ins1e rat cell line and shedding from the cel...More data for this Ligand-Target Pair