BDBM124199 US8748458, 3

SMILES ONC(=O)CCCCCCN(c1ccccn1)c1ccccn1

InChI Key InChIKey=QKTORDWLHYWRJF-UHFFFAOYSA-N

Data  6 IC50

Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 124199   

TargetHistone deacetylase 1(Homo sapiens (Human))
Karus Therapeutics Limited

US Patent
LigandPNGBDBM124199(US8748458, 3)
Show SMILES ONC(=O)CCCCCCN(c1ccccn1)c1ccccn1
Show InChI InChI=1S/C17H22N4O2/c22-17(20-23)11-3-1-2-8-14-21(15-9-4-6-12-18-15)16-10-5-7-13-19-16/h4-7,9-10,12-13,23H,1-3,8,11,14H2,(H,20,22)
Affinity DataIC50: 458nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
Karus Therapeutics Limited

US Patent
LigandPNGBDBM124199(US8748458, 3)
Show SMILES ONC(=O)CCCCCCN(c1ccccn1)c1ccccn1
Show InChI InChI=1S/C17H22N4O2/c22-17(20-23)11-3-1-2-8-14-21(15-9-4-6-12-18-15)16-10-5-7-13-19-16/h4-7,9-10,12-13,23H,1-3,8,11,14H2,(H,20,22)
Affinity DataIC50: 1.54E+3nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Karus Therapeutics Limited

US Patent
LigandPNGBDBM124199(US8748458, 3)
Show SMILES ONC(=O)CCCCCCN(c1ccccn1)c1ccccn1
Show InChI InChI=1S/C17H22N4O2/c22-17(20-23)11-3-1-2-8-14-21(15-9-4-6-12-18-15)16-10-5-7-13-19-16/h4-7,9-10,12-13,23H,1-3,8,11,14H2,(H,20,22)
Affinity DataIC50: 9nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
TargetHistone deacetylase 4(Homo sapiens (Human))
Karus Therapeutics Limited

US Patent
LigandPNGBDBM124199(US8748458, 3)
Show SMILES ONC(=O)CCCCCCN(c1ccccn1)c1ccccn1
Show InChI InChI=1S/C17H22N4O2/c22-17(20-23)11-3-1-2-8-14-21(15-9-4-6-12-18-15)16-10-5-7-13-19-16/h4-7,9-10,12-13,23H,1-3,8,11,14H2,(H,20,22)
Affinity DataIC50: 307nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
TargetHistone deacetylase 5(Homo sapiens (Human))
Karus Therapeutics Limited

US Patent
LigandPNGBDBM124199(US8748458, 3)
Show SMILES ONC(=O)CCCCCCN(c1ccccn1)c1ccccn1
Show InChI InChI=1S/C17H22N4O2/c22-17(20-23)11-3-1-2-8-14-21(15-9-4-6-12-18-15)16-10-5-7-13-19-16/h4-7,9-10,12-13,23H,1-3,8,11,14H2,(H,20,22)
Affinity DataIC50: 458nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
TargetHistone deacetylase 3(Homo sapiens (Human))
Karus Therapeutics Limited

US Patent
LigandPNGBDBM124199(US8748458, 3)
Show SMILES ONC(=O)CCCCCCN(c1ccccn1)c1ccccn1
Show InChI InChI=1S/C17H22N4O2/c22-17(20-23)11-3-1-2-8-14-21(15-9-4-6-12-18-15)16-10-5-7-13-19-16/h4-7,9-10,12-13,23H,1-3,8,11,14H2,(H,20,22)
Affinity DataIC50: 710nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair