BDBM124424 US8759532, 77
SMILES COc1ccc(CCNC(=O)c2cccnc2Oc2ccc(Nc3nc4ccccc4s3)cc2)cc1
InChI Key InChIKey=DXWXWZFKYAEOAV-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 124424
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Amgen
US Patent
Amgen
US Patent
Affinity DataIC50: 2.47nMT: 2°CAssay Description:To check the inhibition profile, 5 μL of serial diluted compounds were incubated with 5 μL of diluted PDE10 enzyme (BPS Bioscience, San Die...More data for this Ligand-Target Pair