BDBM124432 US8759532, 85
SMILES N(c1nc2ccccc2[nH]1)c1ccc(Oc2ncccc2-c2cccnc2)cc1
InChI Key InChIKey=JHDROVNZPSKKFY-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 124432
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Amgen
US Patent
Amgen
US Patent
Affinity DataIC50: 0.179nMT: 2°CAssay Description:To check the inhibition profile, 5 μL of serial diluted compounds were incubated with 5 μL of diluted PDE10 enzyme (BPS Bioscience, San Die...More data for this Ligand-Target Pair