BDBM124781 US8765940, 1-(7-fluoro-3-methyl-2-(2-pyridinyl)-4-quinolinyl)-6-(4-morpholinyl)-1,2,2',3',5',6'-hexahydrospiro[indole-3,4'-thiopyran]-1',1'-dioxide
SMILES Cc1c(nc2cc(F)ccc2c1N1CC2(CCS(=O)(=O)CC2)c2ccc(cc12)N1CCOCC1)-c1ccccn1
InChI Key InChIKey=KILCNCDDYMFDOD-UHFFFAOYSA-N
Data 1 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 124781
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Amgen
US Patent
Amgen
US Patent
Affinity DataKi: 1.37nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair