BDBM125259 US8772480, 71

SMILES COc1ccc(COCc2cnc(Nc3cccc4[nH]ccc34)c(-c3nc(C)nc4nc[nH]c34)c2)cc1

InChI Key InChIKey=FUNSNPXGCRBIGZ-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 125259   

LigandChemical structure of BindingDB Monomer ID 125259BDBM125259(US8772480, 71)
Affinity DataKi:  402nMAssay Description:The PI3K AlphaScreen assay (PerkinElmer, Waltham, Mass.) measures the activity of a panel of four phosphoinositide 3-kinases: PI3Kalpha, PI3Kbeta, PI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 125259BDBM125259(US8772480, 71)
Affinity DataIC50: 5.00E+4nMAssay Description:The Invitrogen (Carlsbad, Calif.) mammalian target of rapamycin (mTOR) Lanthascreen assay can be used to quantitate mTOR kinase activity in an in vit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
US Patent