BDBM125260 US8772480, 72

SMILES Cc1nc(-c2cc(CO)cnc2Nc2cccc3[nH]ncc23)c2[nH]cnc2n1

InChI Key InChIKey=WWZQMWJGKGAIBX-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 125260   

LigandChemical structure of BindingDB Monomer ID 125260BDBM125260(US8772480, 72)
Affinity DataKi:  33nMAssay Description:The PI3K AlphaScreen assay (PerkinElmer, Waltham, Mass.) measures the activity of a panel of four phosphoinositide 3-kinases: PI3Kalpha, PI3Kbeta, PI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 125260BDBM125260(US8772480, 72)
Affinity DataIC50: 2.75E+3nMAssay Description:The Invitrogen (Carlsbad, Calif.) mammalian target of rapamycin (mTOR) Lanthascreen assay can be used to quantitate mTOR kinase activity in an in vit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
US Patent