BDBM12576 Bisphosphonate 1::CHEMBL923::JMC515594 Compound 64::RIS::Risdronate::US11279719, Example Risedronic acid RIS::[1-hydroxy-1-phosphono-2-(pyridin-3-yl)ethyl]phosphonic acid

SMILES: c1cc(cnc1)CC(O)(P(=O)(O)O)P(=O)(O)O

InChI Key: InChIKey=IIDJRNMFWXDHID-UHFFFAOYSA-N

Data: 7 KI  38 IC50  1 EC50  2 ITC

PDB links: 19 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 45 hits for monomerid = 12576   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Farnesyl pyrophosphate synthase (Human)	BDBM12576 (JMC515594 Compound 64 | Risdronate | CHEMBL923 | R...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	860	n/a	n/a	n/a	n/a	n/a	n/a
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Farnesyl diphosphate synthase (Toxoplasma gondii)	BDBM12576 (JMC515594 Compound 64 | Risdronate | CHEMBL923 | R...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	74	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Farnesyl pyrophosphate synthase (Human)	BDBM12576 (JMC515594 Compound 64 | Risdronate | CHEMBL923 | R...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
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H(+)-exporting diphosphatase (Trypanosoma brucei)	BDBM12576 (JMC515594 Compound 64 | Risdronate | CHEMBL923 | R...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.57E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Farnesyl pyrophosphate synthase (Human)	BDBM12576 (JMC515594 Compound 64 | Risdronate | CHEMBL923 | R...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	453	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Farnesyl pyrophosphate synthase (Human)	BDBM12576 (JMC515594 Compound 64 | Risdronate | CHEMBL923 | R...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Farnesyl pyrophosphate synthase (Human)	BDBM12576 (JMC515594 Compound 64 | Risdronate | CHEMBL923 | R...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Farnesyl pyrophosphate synthase (Human)	BDBM12576 (JMC515594 Compound 64 | Risdronate | CHEMBL923 | R...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Farnesyl pyrophosphate synthase (Human)	BDBM12576 (JMC515594 Compound 64 | Risdronate | CHEMBL923 | R...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Geranylgeranyl pyrophosphate synthase (Human)	BDBM12576 (JMC515594 Compound 64 | Risdronate | CHEMBL923 | R...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Farnesyl diphosphate synthase (Trypanosoma cruzi)	BDBM12576 (JMC515594 Compound 64 | Risdronate | CHEMBL923 | R...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Farnesyl pyrophosphate synthase (Human)	BDBM12576 (JMC515594 Compound 64 | Risdronate | CHEMBL923 | R...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Farnesyl pyrophosphate synthase (Human)	BDBM12576 (JMC515594 Compound 64 | Risdronate | CHEMBL923 | R...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Farnesyl diphosphate synthase (Trypanosoma cruzi)	BDBM12576 (JMC515594 Compound 64 | Risdronate | CHEMBL923 | R...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Farnesyl diphosphate synthase (Toxoplasma gondii)	BDBM12576 (JMC515594 Compound 64 | Risdronate | CHEMBL923 | R...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	74	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Farnesyl pyrophosphate synthase (Human)	BDBM12576 (JMC515594 Compound 64 | Risdronate | CHEMBL923 | R...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Farnesyl pyrophosphate synthase (Human)	BDBM12576 (JMC515594 Compound 64 | Risdronate | CHEMBL923 | R...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Farnesyl diphosphate synthase (Toxoplasma gondii)	BDBM12576 (JMC515594 Compound 64 | Risdronate | CHEMBL923 | R...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	74	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Farnesyl pyrophosphate synthase (Human)	BDBM12576 (JMC515594 Compound 64 | Risdronate | CHEMBL923 | R...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Farnesyl pyrophosphate synthase (Human)	BDBM12576 (JMC515594 Compound 64 | Risdronate | CHEMBL923 | R...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Geranylgeranyl pyrophosphate synthase (Human)	BDBM12576 (JMC515594 Compound 64 | Risdronate | CHEMBL923 | R...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.31E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Geranylgeranyl pyrophosphate synthase (Human)	BDBM12576 (JMC515594 Compound 64 | Risdronate | CHEMBL923 | R...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Farnesyl pyrophosphate synthase (Human)	BDBM12576 (JMC515594 Compound 64 | Risdronate | CHEMBL923 | R...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
4-hydroxy-3-methylbut-2-enyl diphosphate reductase (Aquifex aeolicus (strain VF5))	BDBM12576 (JMC515594 Compound 64 | Risdronate | CHEMBL923 | R...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Farnesyl pyrophosphate synthase (Human)	BDBM12576 (JMC515594 Compound 64 | Risdronate | CHEMBL923 | R...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
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Butyrophilin subfamily 3 member A1 (Human)	BDBM12576 (JMC515594 Compound 64 | Risdronate | CHEMBL923 | R...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	80	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Geranylgeranyl pyrophosphate synthase (Human)	BDBM12576 (JMC515594 Compound 64 | Risdronate | CHEMBL923 | R...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Farnesyl pyrophosphate synthase (Human)	BDBM12576 (JMC515594 Compound 64 | Risdronate | CHEMBL923 | R...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Farnesyl pyrophosphate synthase (Human)	BDBM12576 (JMC515594 Compound 64 | Risdronate | CHEMBL923 | R...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	82	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Farnesyl pyrophosphate synthase (Human)	BDBM12576 (JMC515594 Compound 64 | Risdronate | CHEMBL923 | R...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.360	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Geranylgeranyl pyrophosphate synthase (Human)	BDBM12576 (JMC515594 Compound 64 | Risdronate | CHEMBL923 | R...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.00E+8	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Farnesyl pyrophosphate synthase (Human)	BDBM12576 (JMC515594 Compound 64 | Risdronate | CHEMBL923 | R...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Polyprenyl synthetase family protein (Leishmania donovani)	BDBM12576 (JMC515594 Compound 64 | Risdronate | CHEMBL923 | R...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Farnesyl pyrophosphate synthase (Human)	BDBM12576 (JMC515594 Compound 64 | Risdronate | CHEMBL923 | R...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polyprenyl synthetase family protein (Leishmania donovani)	BDBM12576 (JMC515594 Compound 64 | Risdronate | CHEMBL923 | R...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
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Phosphotransferase (Trypanosoma cruzi)	BDBM12576 (JMC515594 Compound 64 | Risdronate | CHEMBL923 | R...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Farnesyl pyrophosphate synthase (Human)	BDBM12576 (JMC515594 Compound 64 | Risdronate | CHEMBL923 | R...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Farnesyl pyrophosphate synthase (Human)	BDBM12576 (JMC515594 Compound 64 | Risdronate | CHEMBL923 | R...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Farnesyl pyrophosphate synthase (Human)	BDBM12576 (JMC515594 Compound 64 | Risdronate | CHEMBL923 | R...) Show SMILES Show InChI	GoogleScholar	UniChem		0.360	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Putative farnesyl pyrophosphate synthase (Cryptosporidium parvum (strain Iowa II))	BDBM12576 (JMC515594 Compound 64 | Risdronate | CHEMBL923 | R...) Show SMILES Show InChI	GoogleScholar	UniChem		0.380	-13.4	45.7	n/a	n/a	n/a	n/a	7.7	37
TBA									Citation and Details
					More data for this Ligand-Target Pair
Farnesyl pyrophosphate synthase (Human)	BDBM12576 (JMC515594 Compound 64 | Risdronate | CHEMBL923 | R...) Show SMILES Show InChI	GoogleScholar	UniChem		16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Farnesyl pyrophosphate synthase (Leishmania major)	BDBM12576 (JMC515594 Compound 64 | Risdronate | CHEMBL923 | R...) Show SMILES Show InChI	GoogleScholar	UniChem		16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polyprenyl synthetase family protein (Leishmania donovani)	BDBM12576 (JMC515594 Compound 64 | Risdronate | CHEMBL923 | R...) Show SMILES Show InChI	GoogleScholar	UniChem		17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Farnesyl pyrophosphate synthase (Human)	BDBM12576 (JMC515594 Compound 64 | Risdronate | CHEMBL923 | R...) Show SMILES Show InChI	GoogleScholar	UniChem		82.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Geranylgeranyl pyrophosphate synthase (Human)	BDBM12576 (JMC515594 Compound 64 | Risdronate | CHEMBL923 | R...) Show SMILES Show InChI	GoogleScholar	UniChem		8.30E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair