BDBM12581 (3-amino-1-hydroxy-1-phosphonopropyl)phosphonic acid::Bisphosphonate 6::CHEMBL834::JMC515594 Compound 62

SMILES: C(CN)C(O)(P(=O)(O)O)P(=O)(O)O

InChI Key: InChIKey=WRUUGTRCQOWXEG-UHFFFAOYSA-N

Data: 5 KI  9 IC50  1 ITC

PDB links: 9 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 12581   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Geranylgeranyl pyrophosphate synthase (Human)	BDBM12581 (JMC515594 Compound 62 | (3-amino-1-hydroxy-1-phosp...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.82E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Farnesyl pyrophosphate synthase (Human)	BDBM12581 (JMC515594 Compound 62 | (3-amino-1-hydroxy-1-phosp...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
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Geranylgeranyl pyrophosphate synthase (Human)	BDBM12581 (JMC515594 Compound 62 | (3-amino-1-hydroxy-1-phosp...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.80E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Farnesyl pyrophosphate synthase (Human)	BDBM12581 (JMC515594 Compound 62 | (3-amino-1-hydroxy-1-phosp...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Farnesyl pyrophosphate synthase (Human)	BDBM12581 (JMC515594 Compound 62 | (3-amino-1-hydroxy-1-phosp...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.86E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Farnesyl pyrophosphate synthase (Human)	BDBM12581 (JMC515594 Compound 62 | (3-amino-1-hydroxy-1-phosp...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
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Farnesyl pyrophosphate synthase (Human)	BDBM12581 (JMC515594 Compound 62 | (3-amino-1-hydroxy-1-phosp...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.93E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Farnesyl pyrophosphate synthase (Human)	BDBM12581 (JMC515594 Compound 62 | (3-amino-1-hydroxy-1-phosp...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	353	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Farnesyl pyrophosphate synthase (Human)	BDBM12581 (JMC515594 Compound 62 | (3-amino-1-hydroxy-1-phosp...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Farnesyl pyrophosphate synthase (Human)	BDBM12581 (JMC515594 Compound 62 | (3-amino-1-hydroxy-1-phosp...) Show SMILES Show InChI	GoogleScholar	UniChem		55.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Farnesyl pyrophosphate synthase (Human)	BDBM12581 (JMC515594 Compound 62 | (3-amino-1-hydroxy-1-phosp...) Show SMILES Show InChI	GoogleScholar	UniChem		180	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Polyprenyl synthetase family protein (Leishmania donovani)	BDBM12581 (JMC515594 Compound 62 | (3-amino-1-hydroxy-1-phosp...) Show SMILES Show InChI	GoogleScholar	UniChem		190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Farnesyl pyrophosphate synthase (Human)	BDBM12581 (JMC515594 Compound 62 | (3-amino-1-hydroxy-1-phosp...) Show SMILES Show InChI	GoogleScholar	UniChem		331	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Hypoxanthine-guanine phosphoribosyltransferase (Trypanosoma brucei brucei)	BDBM12581 (JMC515594 Compound 62 | (3-amino-1-hydroxy-1-phosp...) Show SMILES Show InChI	GoogleScholar	UniChem		5.06E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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