BindingDB logo
myBDB logout

BDBM125846 US8772305, 241

SMILES: N(c1ccc2ncsc2c1)c1nccc(n1)-c1ccccn1

InChI Key: InChIKey=QYEJFIGORAVYNA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 125846   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase SYK


(Homo sapiens (Human))
BDBM125846
PNG
(US8772305, 241)
Show SMILES N(c1ccc2ncsc2c1)c1nccc(n1)-c1ccccn1
Show InChI InChI=1S/C16H11N5S/c1-2-7-17-12(3-1)13-6-8-18-16(21-13)20-11-4-5-14-15(9-11)22-10-19-14/h1-10H,(H,18,20,21)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 103n/an/an/an/a7.5-80



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...


US Patent US8772305 (2014)


BindingDB Entry DOI: 10.7270/Q2KH0M0H
More data for this
Ligand-Target Pair