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BDBM125975 US8772297, Y140

SMILES: COc1ccccc1NS(=O)(=O)c1cccc(c1)S(=O)(=O)NCC1CCN(CC1)C(=O)OC(C)(C)C

InChI Key: InChIKey=BLIYGGYEOUFANL-UHFFFAOYSA-N

Data: 1 IC50

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   Substructure
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 125975   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
TGF-beta receptor type I


(Homo sapiens (Human))
BDBM125975
PNG
(US8772297, Y140)
Show SMILES COc1ccccc1NS(=O)(=O)c1cccc(c1)S(=O)(=O)NCC1CCN(CC1)C(=O)OC(C)(C)C
Show InChI InChI=1S/C24H33N3O7S2/c1-24(2,3)34-23(28)27-14-12-18(13-15-27)17-25-35(29,30)19-8-7-9-20(16-19)36(31,32)26-21-10-5-6-11-22(21)33-4/h5-11,16,18,25-26H,12-15,17H2,1-4H3
PDB

KEGG

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 3.00E+4n/an/an/an/an/an/a



Kyoto University

US Patent


Assay Description
The biological activity of a compound was determined by measuring the activation of Smad3/Smad4 complex which is a transcription factor showing activ...


US Patent US8772297 (2014)


BindingDB Entry DOI: 10.7270/Q2XS5T2N
More data for this
Ligand-Target Pair