BindingDB logo
myBDB logout

BDBM126326 US8778951, 136

SMILES: NCC1CCN(CC1)c1cccc(n1)-c1cc(N[C@H]2CC[C@H](O)CC2)ncc1Cl

InChI Key: InChIKey=UGLJPEADADUIST-QAQDUYKDNA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 126326   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cyclin-T1


(Homo sapiens (Human))
BDBM126326
PNG
(US8778951, 136)
Show SMILES NCC1CCN(CC1)c1cccc(n1)-c1cc(N[C@H]2CC[C@H](O)CC2)ncc1Cl
Show InChI InChI=1/C22H30ClN5O/c23-19-14-25-21(26-16-4-6-17(29)7-5-16)12-18(19)20-2-1-3-22(27-20)28-10-8-15(13-24)9-11-28/h1-3,12,14-17,29H,4-11,13,24H2,(H,25,26)/t16-,17-
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 0.204n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
Cdk9/cyclinT1 is purchased from Millipore, cat #14-685. The final total protein concentration in the assay 4 nM. The 5TAMRA-cdk7tide peptide substrat...


US Patent US8778951 (2014)


BindingDB Entry DOI: 10.7270/Q25B014T
More data for this
Ligand-Target Pair