BDBM126500 US11591322, Compound NVP-2::US8778951, 310

SMILES: COC[C@@H](C)N[C@H]1CC[C@@H](CC1)Nc1cc(c(Cl)cn1)-c1cccc(NCC2(CCOCC2)C#N)n1

InChI Key: InChIKey=XWQVQSXLXAXOPJ-UHFFFAOYSA-N

Data: 17 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 21 hits for monomerid = 126500   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 7 (Human)	BDBM126500 (US8778951, 310 | US11591322, Compound NVP-2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 7 (Human)	BDBM126500 (US8778951, 310 | US11591322, Compound NVP-2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 2 (Human)	BDBM126500 (US8778951, 310 | US11591322, Compound NVP-2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 9 (Human)	BDBM126500 (US8778951, 310 | US11591322, Compound NVP-2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 9 (Human)	BDBM126500 (US8778951, 310 | US11591322, Compound NVP-2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
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Dual specificity tyrosine-phosphorylation-regulated kinase 1B (Human)	BDBM126500 (US8778951, 310 | US11591322, Compound NVP-2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 18 (Human)	BDBM126500 (US8778951, 310 | US11591322, Compound NVP-2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 17 (Human)	BDBM126500 (US8778951, 310 | US11591322, Compound NVP-2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 16 (Human)	BDBM126500 (US8778951, 310 | US11591322, Compound NVP-2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	605	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 14 (Human)	BDBM126500 (US8778951, 310 | US11591322, Compound NVP-2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.45E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 8 (Human)	BDBM126500 (US8778951, 310 | US11591322, Compound NVP-2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-T1/Cyclin-dependent kinase 9 (Human)	BDBM126500 (US8778951, 310 | US11591322, Compound NVP-2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.000300	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 5 (Human)	BDBM126500 (US8778951, 310 | US11591322, Compound NVP-2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.05E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 2 (Human)	BDBM126500 (US8778951, 310 | US11591322, Compound NVP-2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	706	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 1 (Human)	BDBM126500 (US8778951, 310 | US11591322, Compound NVP-2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	584	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 9 (Human)	BDBM126500 (US8778951, 310 | US11591322, Compound NVP-2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<0.514	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 9 (Human)	BDBM126500 (US8778951, 310 | US11591322, Compound NVP-2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<0.5	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-A2/Cyclin-dependent kinase 2 (Human)	BDBM126500 (US8778951, 310 | US11591322, Compound NVP-2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.46E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-K (Human)	BDBM126500 (US8778951, 310 | US11591322, Compound NVP-2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 6/G1/S-specific cyclin-D3 (Human)	BDBM126500 (US8778951, 310 | US11591322, Compound NVP-2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-T1/Cyclin-dependent kinase 9 (Human)	BDBM126500 (US8778951, 310 | US11591322, Compound NVP-2) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.75	n/a	n/a	n/a	n/a	n/a	n/a
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