BDBM12661 1-(3-Aminobenzisoxazol-5-yl)-3-trifluoromethyl-5-[[4-(2-aminosulfonyl-4-pyridinyl)-3-fluorophenyl]aminocarbonyl]pyrazole, Trifluoroacetic Acid Salt::1-(3-amino-1,2-benzoxazol-5-yl)-N-[2-fluoro-4-(3-sulfamoylpyridin-4-yl)phenyl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide; 2,2,2-trifluoroacetic acid::Razaxaban Analogue::aminobenzisoxazole 23
SMILES Nc1noc2ccc(cc12)-n1nc(cc1C(=O)Nc1ccc(cc1F)-c1ccncc1S(N)(=O)=O)C(F)(F)F
InChI Key InChIKey=SIRYBZWAPDLBNE-UHFFFAOYSA-N
Data 3 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 12661
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Bristol-Myers Squibb Pharmaceutical Research Institute
Affinity DataKi: 0.100nM ΔG°: -13.5kcal/molepH: 7.0 T: 2°CAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
Affinity DataKi: 740nMAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
Affinity DataKi: >4.20E+3nMAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair