BDBM12676 1-(3-Aminobenzisoxazol-5-yl)-3-trifluoromethyl-N-[2-fluoro-4-[(2-dimethylaminomethyl)imidazol-1-yl]phenyl]-1H-pyrazole-5-carboxyamide Hydrochloride Salt::1-(3-amino-1,2-benzoxazol-5-yl)-N-(4-{2-[(dimethylamino)methyl]-1H-imidazol-1-yl}-2-fluorophenyl)-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide::BMS-561389::CHEMBL206335::CHEMBL558198::DPC 906::Razaxaban

SMILES: CN(C)Cc1nccn1-c1ccc(NC(=O)c2cc(nn2-c2ccc3onc(N)c3c2)C(F)(F)F)c(F)c1

InChI Key: InChIKey=OFJRNBWSFXEHSA-UHFFFAOYSA-N

Data: 31 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 31 hits for monomerid = 12676   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Human)	BDBM12676 (DPC 906 | 1-(3-Aminobenzisoxazol-5-yl)-3-trifluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		0.190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Coagulation factor X (Human)	BDBM12676 (DPC 906 | 1-(3-Aminobenzisoxazol-5-yl)-3-trifluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		0.190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Coagulation factor X (Human)	BDBM12676 (DPC 906 | 1-(3-Aminobenzisoxazol-5-yl)-3-trifluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		0.190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Coagulation factor X (Human)	BDBM12676 (DPC 906 | 1-(3-Aminobenzisoxazol-5-yl)-3-trifluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		0.190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Coagulation factor X (Human)	BDBM12676 (DPC 906 | 1-(3-Aminobenzisoxazol-5-yl)-3-trifluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		0.190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Coagulation factor X (Human)	BDBM12676 (DPC 906 | 1-(3-Aminobenzisoxazol-5-yl)-3-trifluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		0.190	-13.1	n/a	n/a	n/a	n/a	n/a	7.0	22
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Coagulation factor X (Human)	BDBM12676 (DPC 906 | 1-(3-Aminobenzisoxazol-5-yl)-3-trifluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		0.190	-13.1	n/a	n/a	n/a	n/a	n/a	7.0	22
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Coagulation factor X (Human)	BDBM12676 (DPC 906 | 1-(3-Aminobenzisoxazol-5-yl)-3-trifluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		0.190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Coagulation factor X (Human)	BDBM12676 (DPC 906 | 1-(3-Aminobenzisoxazol-5-yl)-3-trifluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		0.190	-13.1	n/a	n/a	n/a	n/a	n/a	7.0	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Coagulation factor X (Human)	BDBM12676 (DPC 906 | 1-(3-Aminobenzisoxazol-5-yl)-3-trifluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		0.190	-13.1	n/a	n/a	n/a	n/a	n/a	7.0	22
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Coagulation factor X (Human)	BDBM12676 (DPC 906 | 1-(3-Aminobenzisoxazol-5-yl)-3-trifluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Coagulation factor X (Human)	BDBM12676 (DPC 906 | 1-(3-Aminobenzisoxazol-5-yl)-3-trifluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Prothrombin (Human)	BDBM12676 (DPC 906 | 1-(3-Aminobenzisoxazol-5-yl)-3-trifluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		540	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Prothrombin (Human)	BDBM12676 (DPC 906 | 1-(3-Aminobenzisoxazol-5-yl)-3-trifluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		540	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Prothrombin (Human)	BDBM12676 (DPC 906 | 1-(3-Aminobenzisoxazol-5-yl)-3-trifluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		540	-8.46	n/a	n/a	n/a	n/a	n/a	7.0	22
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Prothrombin (Human)	BDBM12676 (DPC 906 | 1-(3-Aminobenzisoxazol-5-yl)-3-trifluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		540	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Prothrombin (Human)	BDBM12676 (DPC 906 | 1-(3-Aminobenzisoxazol-5-yl)-3-trifluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Plasma kallikrein (Human)	BDBM12676 (DPC 906 | 1-(3-Aminobenzisoxazol-5-yl)-3-trifluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		>2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Plasma kallikrein (Human)	BDBM12676 (DPC 906 | 1-(3-Aminobenzisoxazol-5-yl)-3-trifluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		>2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Prothrombin (Human)	BDBM12676 (DPC 906 | 1-(3-Aminobenzisoxazol-5-yl)-3-trifluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		>6.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Coagulation factor IX (Human)	BDBM12676 (DPC 906 | 1-(3-Aminobenzisoxazol-5-yl)-3-trifluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Coagulation factor IX (Human)	BDBM12676 (DPC 906 | 1-(3-Aminobenzisoxazol-5-yl)-3-trifluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		>9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Serine protease 1 (Bovine)	BDBM12676 (DPC 906 | 1-(3-Aminobenzisoxazol-5-yl)-3-trifluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	>-6.75	n/a	n/a	n/a	n/a	n/a	7.0	22
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Serine protease 1 (Bovine)	BDBM12676 (DPC 906 | 1-(3-Aminobenzisoxazol-5-yl)-3-trifluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Coagulation factor XI (Human)	BDBM12676 (DPC 906 | 1-(3-Aminobenzisoxazol-5-yl)-3-trifluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Coagulation factor VII (Human)	BDBM12676 (DPC 906 | 1-(3-Aminobenzisoxazol-5-yl)-3-trifluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Coagulation factor VII (Human)	BDBM12676 (DPC 906 | 1-(3-Aminobenzisoxazol-5-yl)-3-trifluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.50E+4	>-6.51	n/a	n/a	n/a	n/a	n/a	7.0	22
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Plasminogen (Human)	BDBM12676 (DPC 906 | 1-(3-Aminobenzisoxazol-5-yl)-3-trifluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Coagulation factor IX (Human)	BDBM12676 (DPC 906 | 1-(3-Aminobenzisoxazol-5-yl)-3-trifluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.50E+4	>-6.51	n/a	n/a	n/a	n/a	n/a	7.0	22
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Vitamin K-dependent protein C (Human)	BDBM12676 (DPC 906 | 1-(3-Aminobenzisoxazol-5-yl)-3-trifluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Tissue-type plasminogen activator (Human)	BDBM12676 (DPC 906 | 1-(3-Aminobenzisoxazol-5-yl)-3-trifluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		>3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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