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BDBM127105 US8791272, 1.16

SMILES: Cc1nn(Cc2ccc(NC(=O)c3ccc(Br)cc3C)cc2)c(C)c1CC(O)=O

InChI Key: InChIKey=IZEJCJVVHOAQLL-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 127105   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
G protein-coupled receptor 44


(Homo sapiens (Human))
BDBM127105
PNG
(US8791272, 1.16)
Show SMILES Cc1nn(Cc2ccc(NC(=O)c3ccc(Br)cc3C)cc2)c(C)c1CC(O)=O
Show InChI InChI=1S/C22H22BrN3O3/c1-13-10-17(23)6-9-19(13)22(29)24-18-7-4-16(5-8-18)12-26-15(3)20(11-21(27)28)14(2)25-26/h4-10H,11-12H2,1-3H3,(H,24,29)(H,27,28)
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PC sid
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Similars

US Patent
3.90n/an/an/an/an/an/a7.4n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...


US Patent US8791272 (2014)


BindingDB Entry DOI: 10.7270/Q2GH9GNV
More data for this
Ligand-Target Pair