BDBM127967 US8796310, 12C

SMILES Cc1c(Br)c(Nc2cc(cc[nH+]2)C(F)(F)F)nc(-c2cnc(s2)[C@@]2(O)CCCc3cc(ccc23)C(O)=O)c1Br

InChI Key InChIKey=VVDRPILAKHDJRT-RUZDIDTESA-O

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 127967   

TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM127967(US8796310, 12C)
Affinity DataIC50:  5.69nMpH: 7.5Assay Description:A recombinant GST-hSyk fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-Syk (Cama Bio...More data for this Ligand-Target Pair
In DepthDetails US Patent