BDBM128101 US10206907, Compound 330::US8796457, 1::US9505754, 1

SMILES: CC1(C)CN(C1)C(=O)c1ccc(cc1)-c1cccc2nc(NC(=O)C3CC3)nn12

InChI Key: InChIKey=MPYACSQFXVMWNO-UHFFFAOYSA-N

Data: 12 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 128101   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK1 [850-1154] (Human)	BDBM128101 (US8796457, 1 | US9505754, 1 | US10206907, Compound...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Tyrosine-protein kinase JAK2 [808-1132] (Human)	BDBM128101 (US8796457, 1 | US9505754, 1 | US10206907, Compound...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 [781-1124] (Human)	BDBM128101 (US8796457, 1 | US9505754, 1 | US10206907, Compound...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Human)	BDBM128101 (US8796457, 1 | US9505754, 1 | US10206907, Compound...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.60	n/a	n/a	n/a	n/a	n/a	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 [866-1154] (Human)	BDBM128101 (US8796457, 1 | US9505754, 1 | US10206907, Compound...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.60	n/a	n/a	n/a	n/a	n/a	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 [866-1054] (Human)	BDBM128101 (US8796457, 1 | US9505754, 1 | US10206907, Compound...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 [781-1124] (Human)	BDBM128101 (US8796457, 1 | US9505754, 1 | US10206907, Compound...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	408	n/a	n/a	n/a	n/a	7.5	30
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Non-receptor tyrosine-protein kinase TYK2 [871-1187] (Human)	BDBM128101 (US8796457, 1 | US9505754, 1 | US10206907, Compound...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	219	n/a	n/a	n/a	n/a	7.5	30
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Human)	BDBM128101 (US8796457, 1 | US9505754, 1 | US10206907, Compound...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	108	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Human)	BDBM128101 (US8796457, 1 | US9505754, 1 | US10206907, Compound...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	539	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Human)	BDBM128101 (US8796457, 1 | US9505754, 1 | US10206907, Compound...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Human)	BDBM128101 (US8796457, 1 | US9505754, 1 | US10206907, Compound...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	225	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair