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BDBM128120 US8796297, 2

SMILES: CN(C)CCNc1ccnc(N)n1

InChI Key: InChIKey=VJADDTSYMSFSEM-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 128120   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM128120
PNG
(US8796297, 2)
Show SMILES CN(C)CCNc1ccnc(N)n1
Show InChI InChI=1S/C8H15N5/c1-13(2)6-5-10-7-3-4-11-8(9)12-7/h3-4H,5-6H2,1-2H3,(H3,9,10,11,12)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
20 -9.76n/an/an/an/an/a7.44



AbbVie Inc.

US Patent


Assay Description
The rat H3 receptor was cloned and expressed in cells, and competition binding assays carried out, according to methods previously described (see Esb...


US Patent US8796297 (2014)


BindingDB Entry DOI: 10.7270/Q2ST7NH8
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM128120
PNG
(US8796297, 2)
Show SMILES CN(C)CCNc1ccnc(N)n1
Show InChI InChI=1S/C8H15N5/c1-13(2)6-5-10-7-3-4-11-8(9)12-7/h3-4H,5-6H2,1-2H3,(H3,9,10,11,12)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
53.7 -9.21n/an/an/an/an/a7.44



AbbVie Inc.

US Patent


Assay Description
The rat H3 receptor was cloned and expressed in cells, and competition binding assays carried out, according to methods previously described (see Esb...


US Patent US8796297 (2014)


BindingDB Entry DOI: 10.7270/Q2ST7NH8
More data for this
Ligand-Target Pair