BDBM128284 US8796295, Table 2: Compound: 8

SMILES COc1cccc(NC(=O)c2cc(Cl)cc(Oc3cncnc3)c2)n1

InChI Key InChIKey=ABUZOTKQQBPGAC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 128284   

TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM128284(US8796295, Table 2: Compound: 8)
Affinity DataIC50:  51nMAssay Description:The utility of the compounds in accordance with the present invention as negative allosteric modulators of metabotropic glutamate receptor activity, ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt University

US Patent
LigandPNGBDBM128284(US8796295, Table 2: Compound: 8)
Affinity DataIC50:  65nMAssay Description:The utility of the compounds in accordance with the present invention as negative allosteric modulators of metabotropic glutamate receptor activity, ...More data for this Ligand-Target Pair
In DepthDetails US Patent