BDBM128496 US8796244, 75

SMILES NC1CCN(CC1)c1ccc(nn1)-c1ccn2c(cnc2c1)-c1cccc(NC(=O)NCC(F)(F)F)c1

InChI Key InChIKey=YBVLJFZBRWBLPQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 128496   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM128496(US8796244, 75)
Affinity DataIC50:  8.90nMpH: 8.0 T: 2°CAssay Description:VEGFR2 (from Upstate), prepared at 2x final concentration, was incubated with test compounds, biotinylated Flt3 substrate (biotin-VASSDNEYFYVDF) (Cel...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM128496(US8796244, 75)
Affinity DataIC50:  0.535nMpH: 8.0 T: 2°CAssay Description:Enzymes (from Upstate) were prepared at 2× final concentration in 1× kinase assay buffer (Table 1). Enzymes were then incubated with test compounds, ...More data for this Ligand-Target Pair
In DepthDetails US Patent