BDBM128579 US8796244, 166

SMILES Nc1nc(ncc1F)-c1ccn2c(cnc2c1)-c1cccc(NC(=O)NC2CC2)c1

InChI Key InChIKey=ZSXOFYFJBPXCMC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 128579   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM128579(US8796244, 166)
Affinity DataIC50:  574nMpH: 8.0 T: 2°CAssay Description:VEGFR2 (from Upstate), prepared at 2x final concentration, was incubated with test compounds, biotinylated Flt3 substrate (biotin-VASSDNEYFYVDF) (Cel...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM128579(US8796244, 166)
Affinity DataIC50:  34.9nMpH: 8.0 T: 2°CAssay Description:Enzymes (from Upstate) were prepared at 2× final concentration in 1× kinase assay buffer (Table 1). Enzymes were then incubated with test compounds, ...More data for this Ligand-Target Pair
In DepthDetails US Patent