BDBM128659 US8796244, 250

SMILES FC(F)(F)CNC(=O)Nc1cccc(c1)-c1cnc2cc(ccn12)-c1nnc(NC2CC2)s1

InChI Key InChIKey=IBSMXTBTUWUZJT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 128659   

TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM128659(US8796244, 250)
Affinity DataIC50:  4.60nMpH: 8.0 T: 2°CAssay Description:Enzymes (from Upstate) were prepared at 2× final concentration in 1× kinase assay buffer (Table 1). Enzymes were then incubated with test compounds, ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM128659(US8796244, 250)
Affinity DataIC50:  14nMpH: 8.0 T: 2°CAssay Description:VEGFR2 (from Upstate), prepared at 2x final concentration, was incubated with test compounds, biotinylated Flt3 substrate (biotin-VASSDNEYFYVDF) (Cel...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM128659(US8796244, 250)
Affinity DataIC50:  0.5nMpH: 8.0 T: 2°CAssay Description:Enzymes (from Upstate) were prepared at 2× final concentration in 1× kinase assay buffer (Table 1). Enzymes were then incubated with test compounds, ...More data for this Ligand-Target Pair
In DepthDetails US Patent