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BDBM128872 US8802711, 41

SMILES: FC(F)(F)c1ccc(cc1)[C@H]1CC[C@@H](C1)NC(=O)Nc1cccc2[nH]ncc12

InChI Key: InChIKey=NKALKRMYMAIVGL-ZFWWWQNUSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 128872   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))
BDBM128872
PNG
(US8802711, 41)
Show SMILES FC(F)(F)c1ccc(cc1)[C@H]1CC[C@@H](C1)NC(=O)Nc1cccc2[nH]ncc12
Show InChI InChI=1S/C20H19F3N4O/c21-20(22,23)14-7-4-12(5-8-14)13-6-9-15(10-13)25-19(28)26-17-2-1-3-18-16(17)11-24-27-18/h1-5,7-8,11,13,15H,6,9-10H2,(H,24,27)(H2,25,26,28)/t13-,15-/m0/s1
PDB
MMDB

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Similars

US Patent
n/an/a 311n/an/an/an/an/an/a



AbbVie Inc

US Patent


Assay Description
The functional activity of compounds at the TRPV1 receptor was determined by measurement of intracellular Ca2+ levels ([Ca2+]i) using the Fluorescenc...


US Patent US8802711 (2014)


BindingDB Entry DOI: 10.7270/Q2QZ28NC
More data for this
Ligand-Target Pair