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BDBM128921 US8802711, 90

SMILES: O[C@@H]1Cc2cccc(NC(=O)N[C@@H]3CC[C@H](C3)c3cccc(F)c3)c2C1

InChI Key: InChIKey=HQLJSFBVHMPCSV-ZTFGCOKTSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 128921   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))
BDBM128921
PNG
(US8802711, 90)
Show SMILES O[C@@H]1Cc2cccc(NC(=O)N[C@@H]3CC[C@H](C3)c3cccc(F)c3)c2C1
Show InChI InChI=1S/C21H23FN2O2/c22-16-5-1-3-13(9-16)14-7-8-17(10-14)23-21(26)24-20-6-2-4-15-11-18(25)12-19(15)20/h1-6,9,14,17-18,25H,7-8,10-12H2,(H2,23,24,26)/t14-,17-,18-/m1/s1
PDB
MMDB

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PC sid
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Similars

US Patent
n/an/a 109n/an/an/an/an/an/a



AbbVie Inc

US Patent


Assay Description
The functional activity of compounds at the TRPV1 receptor was determined by measurement of intracellular Ca2+ levels ([Ca2+]i) using the Fluorescenc...


US Patent US8802711 (2014)


BindingDB Entry DOI: 10.7270/Q2QZ28NC
More data for this
Ligand-Target Pair