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BDBM128948 US8802711, 118

SMILES: Cn1c2cccc(NC(=O)N[C@H]3CC[C@@H](C3)c3ccccc3)c2ccc1=O

InChI Key: InChIKey=ADHPABPSTJYXKJ-IRXDYDNUSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 128948   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))
BDBM128948
PNG
(US8802711, 118)
Show SMILES Cn1c2cccc(NC(=O)N[C@H]3CC[C@@H](C3)c3ccccc3)c2ccc1=O
Show InChI InChI=1S/C22H23N3O2/c1-25-20-9-5-8-19(18(20)12-13-21(25)26)24-22(27)23-17-11-10-16(14-17)15-6-3-2-4-7-15/h2-9,12-13,16-17H,10-11,14H2,1H3,(H2,23,24,27)/t16-,17-/m0/s1
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Similars

US Patent
n/an/a>3.75E+4n/an/an/an/an/an/a



AbbVie Inc

US Patent


Assay Description
The functional activity of compounds at the TRPV1 receptor was determined by measurement of intracellular Ca2+ levels ([Ca2+]i) using the Fluorescenc...


US Patent US8802711 (2014)


BindingDB Entry DOI: 10.7270/Q2QZ28NC
More data for this
Ligand-Target Pair