BDBM12915 2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one::2-(morpholin-4-yl)-8-phenyl-4H-chromen-4-one::CHEMBL98350::LY294002::US10308662, Compound LY294002::US9505780, LY294002

SMILES: O=c1cc(oc2c(cccc12)-c1ccccc1)N1CCOCC1

InChI Key: InChIKey=CZQHHVNHHHRRDU-UHFFFAOYSA-N

Data: 8 KI  151 IC50  1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 171 hits for monomerid = 12915   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Human)	BDBM12915 (CHEMBL98350 | 2-(morpholin-4-yl)-8-phenyl-4H-chrom...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	7.6	30
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Human)	BDBM12915 (CHEMBL98350 | 2-(morpholin-4-yl)-8-phenyl-4H-chrom...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40E+3	210	n/a	n/a	n/a	7.2	20
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Human)	BDBM12915 (CHEMBL98350 | 2-(morpholin-4-yl)-8-phenyl-4H-chrom...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	630	n/a	n/a	n/a	n/a	7.4	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Human)	BDBM12915 (CHEMBL98350 | 2-(morpholin-4-yl)-8-phenyl-4H-chrom...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	340	n/a	n/a	n/a	n/a	7.4	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Human)	BDBM12915 (CHEMBL98350 | 2-(morpholin-4-yl)-8-phenyl-4H-chrom...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	7.4	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta (Human)	BDBM12915 (CHEMBL98350 | 2-(morpholin-4-yl)-8-phenyl-4H-chrom...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	7.4	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Human)	BDBM12915 (CHEMBL98350 | 2-(morpholin-4-yl)-8-phenyl-4H-chrom...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	630	n/a	n/a	n/a	n/a	7.4	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Human)	BDBM12915 (CHEMBL98350 | 2-(morpholin-4-yl)-8-phenyl-4H-chrom...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	340	n/a	n/a	n/a	n/a	7.4	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Human)	BDBM12915 (CHEMBL98350 | 2-(morpholin-4-yl)-8-phenyl-4H-chrom...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	7.4	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta (Human)	BDBM12915 (CHEMBL98350 | 2-(morpholin-4-yl)-8-phenyl-4H-chrom...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	7.4	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform/Phosphoinositide 3-kinase regulatory subunit 5 (Human)	BDBM12915 (CHEMBL98350 | 2-(morpholin-4-yl)-8-phenyl-4H-chrom...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.72E+3	n/a	n/a	n/a	n/a	7.4	30
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Human)	BDBM12915 (CHEMBL98350 | 2-(morpholin-4-yl)-8-phenyl-4H-chrom...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.30E+3	n/a	n/a	n/a	n/a	7.4	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Human)	BDBM12915 (CHEMBL98350 | 2-(morpholin-4-yl)-8-phenyl-4H-chrom...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	561	n/a	n/a	n/a	n/a	7.4	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Human)	BDBM12915 (CHEMBL98350 | 2-(morpholin-4-yl)-8-phenyl-4H-chrom...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.70E+3	n/a	n/a	n/a	n/a	7.4	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Human)	BDBM12915 (CHEMBL98350 | 2-(morpholin-4-yl)-8-phenyl-4H-chrom...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	858	n/a	n/a	n/a	n/a	7.4	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 [44-167] (Human)	BDBM12915 (CHEMBL98350 | 2-(morpholin-4-yl)-8-phenyl-4H-chrom...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.33E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 [349-460] (Human)	BDBM12915 (CHEMBL98350 | 2-(morpholin-4-yl)-8-phenyl-4H-chrom...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.31E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha (Human)	BDBM12915 (CHEMBL98350 | 2-(morpholin-4-yl)-8-phenyl-4H-chrom...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	356	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit beta (Human)	BDBM12915 (CHEMBL98350 | 2-(morpholin-4-yl)-8-phenyl-4H-chrom...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	736	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Human)	BDBM12915 (CHEMBL98350 | 2-(morpholin-4-yl)-8-phenyl-4H-chrom...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.22E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Human)	BDBM12915 (CHEMBL98350 | 2-(morpholin-4-yl)-8-phenyl-4H-chrom...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.06E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 [75-147] (Human)	BDBM12915 (CHEMBL98350 | 2-(morpholin-4-yl)-8-phenyl-4H-chrom...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.33E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 [368-440] (Human)	BDBM12915 (CHEMBL98350 | 2-(morpholin-4-yl)-8-phenyl-4H-chrom...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.31E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Human)	BDBM12915 (CHEMBL98350 | 2-(morpholin-4-yl)-8-phenyl-4H-chrom...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	356	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Human)	BDBM12915 (CHEMBL98350 | 2-(morpholin-4-yl)-8-phenyl-4H-chrom...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	736	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Human)	BDBM12915 (CHEMBL98350 | 2-(morpholin-4-yl)-8-phenyl-4H-chrom...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.22E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Human)	BDBM12915 (CHEMBL98350 | 2-(morpholin-4-yl)-8-phenyl-4H-chrom...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.06E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Human)	BDBM12915 (CHEMBL98350 | 2-(morpholin-4-yl)-8-phenyl-4H-chrom...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Human)	BDBM12915 (CHEMBL98350 | 2-(morpholin-4-yl)-8-phenyl-4H-chrom...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	980	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Human)	BDBM12915 (CHEMBL98350 | 2-(morpholin-4-yl)-8-phenyl-4H-chrom...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.36E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Human)	BDBM12915 (CHEMBL98350 | 2-(morpholin-4-yl)-8-phenyl-4H-chrom...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	940	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Human)	BDBM12915 (CHEMBL98350 | 2-(morpholin-4-yl)-8-phenyl-4H-chrom...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Human)	BDBM12915 (CHEMBL98350 | 2-(morpholin-4-yl)-8-phenyl-4H-chrom...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.36E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Human)	BDBM12915 (CHEMBL98350 | 2-(morpholin-4-yl)-8-phenyl-4H-chrom...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Human)	BDBM12915 (CHEMBL98350 | 2-(morpholin-4-yl)-8-phenyl-4H-chrom...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	950	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Human)	BDBM12915 (CHEMBL98350 | 2-(morpholin-4-yl)-8-phenyl-4H-chrom...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Human)	BDBM12915 (CHEMBL98350 | 2-(morpholin-4-yl)-8-phenyl-4H-chrom...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	980	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA-dependent protein kinase catalytic subunit (Human)	BDBM12915 (CHEMBL98350 | 2-(morpholin-4-yl)-8-phenyl-4H-chrom...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Human)	BDBM12915 (CHEMBL98350 | 2-(morpholin-4-yl)-8-phenyl-4H-chrom...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.18E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Human)	BDBM12915 (CHEMBL98350 | 2-(morpholin-4-yl)-8-phenyl-4H-chrom...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Human)	BDBM12915 (CHEMBL98350 | 2-(morpholin-4-yl)-8-phenyl-4H-chrom...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	970	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Human)	BDBM12915 (CHEMBL98350 | 2-(morpholin-4-yl)-8-phenyl-4H-chrom...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	570	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA-dependent protein kinase catalytic subunit (Human)	BDBM12915 (CHEMBL98350 | 2-(morpholin-4-yl)-8-phenyl-4H-chrom...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cGMP-dependent 3',5'-cyclic phosphodiesterase (Human)	BDBM12915 (CHEMBL98350 | 2-(morpholin-4-yl)-8-phenyl-4H-chrom...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Human)	BDBM12915 (CHEMBL98350 | 2-(morpholin-4-yl)-8-phenyl-4H-chrom...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Human)	BDBM12915 (CHEMBL98350 | 2-(morpholin-4-yl)-8-phenyl-4H-chrom...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA-dependent protein kinase catalytic subunit (Human)	BDBM12915 (CHEMBL98350 | 2-(morpholin-4-yl)-8-phenyl-4H-chrom...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Human)	BDBM12915 (CHEMBL98350 | 2-(morpholin-4-yl)-8-phenyl-4H-chrom...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Human)	BDBM12915 (CHEMBL98350 | 2-(morpholin-4-yl)-8-phenyl-4H-chrom...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine-protein kinase ATM (Human)	BDBM12915 (CHEMBL98350 | 2-(morpholin-4-yl)-8-phenyl-4H-chrom...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair