BDBM129374 US8802673, 16

SMILES N#Cc1cnc(Nc2ccc(cc2)[C@H]2CNCCO2)nc1

InChI Key InChIKey=LQKRWYFWHIWOMV-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 129374   

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandPNGBDBM129374(US8802673, 16)
Affinity DataKi:  27.6nM ΔG°:  -10.7kcal/molepH: 7.4 T: 2°CAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2015
Entry Details
US Patent

TargetTrace amine-associated receptor 7b(Rat)
Hoffmann-La Roche

US Patent
LigandPNGBDBM129374(US8802673, 16)
Affinity DataKi:  448nM ΔG°:  -9.00kcal/molepH: 7.4 T: 2°CAssay Description:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2015
Entry Details
US Patent