BDBM129423 US8802673, 65

SMILES C1Oc2ccc(Nc3ccc(cc3)[C@H]3CNCCO3)cc2O1

InChI Key InChIKey=LFWYZARXTBIWQA-QGZVFWFLSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 129423   

TargetTrace amine-associated receptor 1(Mus musculus (Mouse))
Hoffmann-La Roche

US Patent
LigandPNGBDBM129423(US8802673, 65)
Affinity DataKi:  13.1nM ΔG°:  -11.2kcal/molepH: 7.4 T: 2°CAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTrace amine-associated receptor 7b(Rattus norvegicus (Rat))
Hoffmann-La Roche

US Patent
LigandPNGBDBM129423(US8802673, 65)
Affinity DataKi:  629nM ΔG°:  -8.79kcal/molepH: 7.4 T: 2°CAssay Description:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent