BDBM12985 5-Amido-pyrrolopyrazole 9d::CHEMBL402548::N-{5-[(2R)-2-methoxy-2-phenylacetyl]-1H,4H,5H,6H-pyrrolo[3,4-c]pyrazol-3-yl}-4-(4-methylpiperazin-1-yl)benzamide
SMILES CO[C@@H](C(=O)N1Cc2n[nH]c(NC(=O)c3ccc(cc3)N3CCN(C)CC3)c2C1)c1ccccc1
InChI Key InChIKey=XKFTZKGMDDZMJI-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 16 hits for monomerid = 12985
Affinity DataIC50: 7.90nMAssay Description:Inhibition of ABL1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of aurora A (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of Aurora A (unknown origin) by biochemical kinase assayMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Inhibition of Aurora A kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of Aurora A kinase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 13nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
TargetAurora kinase B(Human)
The Key Laboratory of Chemistry For Natural Products of Guizhou Province and Chinese Academy of Sciences
Curated by ChEMBL
The Key Laboratory of Chemistry For Natural Products of Guizhou Province and Chinese Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of Aurora B (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 61nMAssay Description:Inhibition of Aurora C kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 61nMAssay Description:Inhibition of aurora C (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 61nMAssay Description:Inhibition of Aurora C kinase (unknown origin)More data for this Ligand-Target Pair
TargetAurora kinase B(Human)
The Key Laboratory of Chemistry For Natural Products of Guizhou Province and Chinese Academy of Sciences
Curated by ChEMBL
The Key Laboratory of Chemistry For Natural Products of Guizhou Province and Chinese Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 79nMAssay Description:Inhibition of recombinant aurora B (unknown origin)More data for this Ligand-Target Pair
TargetAurora kinase B(Human)
The Key Laboratory of Chemistry For Natural Products of Guizhou Province and Chinese Academy of Sciences
Curated by ChEMBL
The Key Laboratory of Chemistry For Natural Products of Guizhou Province and Chinese Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 79nMAssay Description:Inhibition of Aurora B (unknown origin) by biochemical kinase assayMore data for this Ligand-Target Pair
TargetAurora kinase B(Human)
The Key Laboratory of Chemistry For Natural Products of Guizhou Province and Chinese Academy of Sciences
Curated by ChEMBL
The Key Laboratory of Chemistry For Natural Products of Guizhou Province and Chinese Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 79nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
TargetAurora kinase B(Human)
The Key Laboratory of Chemistry For Natural Products of Guizhou Province and Chinese Academy of Sciences
Curated by ChEMBL
The Key Laboratory of Chemistry For Natural Products of Guizhou Province and Chinese Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 79nMAssay Description:Inhibition of aurora B kinaseMore data for this Ligand-Target Pair
TargetAurora kinase B(Human)
The Key Laboratory of Chemistry For Natural Products of Guizhou Province and Chinese Academy of Sciences
Curated by ChEMBL
The Key Laboratory of Chemistry For Natural Products of Guizhou Province and Chinese Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 79nMAssay Description:Inhibition of aurora B (unknown origin)More data for this Ligand-Target Pair
TargetAurora kinase B(Human)
The Key Laboratory of Chemistry For Natural Products of Guizhou Province and Chinese Academy of Sciences
Curated by ChEMBL
The Key Laboratory of Chemistry For Natural Products of Guizhou Province and Chinese Academy of Sciences
Curated by ChEMBL
Affinity DataKi: 79nMAssay Description:Inhibition of Aurora B kinaseMore data for this Ligand-Target Pair