BDBM12987 5-Amido-pyrrolopyrazole 9f::CHEMBL384575::N-{5-[(2S)-2-methoxy-2-phenylacetyl]-1H,4H,5H,6H-pyrrolo[3,4-c]pyrazol-3-yl}-4-(4-methylpiperazin-1-yl)benzamide
SMILES CO[C@H](C(=O)N1Cc2n[nH]c(NC(=O)c3ccc(cc3)N3CCN(C)CC3)c2C1)c1ccccc1
InChI Key InChIKey=XKFTZKGMDDZMJI-QHCPKHFHSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 12987
Affinity DataIC50: 354nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
Affinity DataIC50: 630nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
Affinity DataIC50: 354nMAssay Description:Inhibition of aurora A kinaseChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 630nMAssay Description:Inhibition of aurora B kinaseChecked by AuthorMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
The First People'S Hospital Of Hangzhou
Curated by ChEMBL
The First People'S Hospital Of Hangzhou
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of BCR-ABL kinase (unknown origin)More data for this Ligand-Target Pair