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BDBM130189 US8815891, 108

SMILES: COc1cc(CN2CCC(CC2)N2CCOCC2)cc2[nH]c(=O)c3CCCNc3c12

InChI Key: InChIKey=POZFIPZQPRMMSS-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 130189   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
PARP 1, 2 and 3


(Homo sapiens (Human))
BDBM130189
PNG
(US8815891, 108)
Show SMILES COc1cc(CN2CCC(CC2)N2CCOCC2)cc2[nH]c(=O)c3CCCNc3c12
Show InChI InChI=1S/C23H32N4O3/c1-29-20-14-16(13-19-21(20)22-18(23(28)25-19)3-2-6-24-22)15-26-7-4-17(5-8-26)27-9-11-30-12-10-27/h13-14,17,24H,2-12,15H2,1H3,(H,25,28)
PDB
MMDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 140n/an/an/an/a7.425



Jeil Pharmaceutical Co., Ltd

US Patent


Assay Description
The activity of the compounds according to the present invention to inhibit the PARP-1 enzyme was examined using a PARP Assay kit (4671-096-K) purcha...


US Patent US8815891 (2014)


BindingDB Entry DOI: 10.7270/Q2SQ8Z3Z
More data for this
Ligand-Target Pair