BDBM13054 (2R,4R)-4-(ethylamino)-2-methyl-1,1-dioxo-2H,3H,4H-1,7-thieno[2,3-b]thiopyran-6-sulfonamide::Dorzolamide, DZA::sulfonamide 5

SMILES: CCN[C@@H]1C[C@@H](C)S(=O)(=O)c2sc(cc12)S(N)(=O)=O

InChI Key: InChIKey=IAVUPMFITXYVAF-UHFFFAOYSA-N

Data: 13 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 13054   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 7 (Human)	BDBM13054 (Dorzolamide, DZA | (2R,4R)-4-(ethylamino)-2-methyl...) Show SMILES Show InChI	GoogleScholar	UniChem		3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 12 (Human)	BDBM13054 (Dorzolamide, DZA | (2R,4R)-4-(ethylamino)-2-methyl...) Show SMILES Show InChI	GoogleScholar	UniChem		3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 2 (Human)	BDBM13054 (Dorzolamide, DZA | (2R,4R)-4-(ethylamino)-2-methyl...) Show SMILES Show InChI	GoogleScholar	UniChem		9	-10.9	n/a	n/a	n/a	n/a	n/a	7.5	22
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Carbonic anhydrase 2 (Human)	BDBM13054 (Dorzolamide, DZA | (2R,4R)-4-(ethylamino)-2-methyl...) Show SMILES Show InChI	GoogleScholar	UniChem		9	-10.8	n/a	n/a	n/a	n/a	n/a	7.5	20
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Carbonic anhydrase 6 (Human)	BDBM13054 (Dorzolamide, DZA | (2R,4R)-4-(ethylamino)-2-methyl...) Show SMILES Show InChI	GoogleScholar	UniChem		10	-10.7	n/a	n/a	n/a	n/a	n/a	7.5	20
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Carbonic anhydrase 13 (Mouse)	BDBM13054 (Dorzolamide, DZA | (2R,4R)-4-(ethylamino)-2-methyl...) Show SMILES Show InChI	GoogleScholar	UniChem		18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 14 (Human)	BDBM13054 (Dorzolamide, DZA | (2R,4R)-4-(ethylamino)-2-methyl...) Show SMILES Show InChI	GoogleScholar	UniChem		27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 5B, mitochondrial (Human)	BDBM13054 (Dorzolamide, DZA | (2R,4R)-4-(ethylamino)-2-methyl...) Show SMILES Show InChI	GoogleScholar	UniChem		33	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 5A, mitochondrial (Human)	BDBM13054 (Dorzolamide, DZA | (2R,4R)-4-(ethylamino)-2-methyl...) Show SMILES Show InChI	GoogleScholar	UniChem		42	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 9 (Human)	BDBM13054 (Dorzolamide, DZA | (2R,4R)-4-(ethylamino)-2-methyl...) Show SMILES Show InChI	GoogleScholar	UniChem		52	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 4 (Human)	BDBM13054 (Dorzolamide, DZA | (2R,4R)-4-(ethylamino)-2-methyl...) Show SMILES Show InChI	GoogleScholar	UniChem		8.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 1 (Human)	BDBM13054 (Dorzolamide, DZA | (2R,4R)-4-(ethylamino)-2-methyl...) Show SMILES Show InChI	GoogleScholar	UniChem		5.00E+4	-5.80	n/a	n/a	n/a	n/a	n/a	7.5	22
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Carbonic anhydrase 1 (Human)	BDBM13054 (Dorzolamide, DZA | (2R,4R)-4-(ethylamino)-2-methyl...) Show SMILES Show InChI	GoogleScholar	UniChem		5.00E+4	-5.77	n/a	n/a	n/a	n/a	n/a	7.5	20
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