BindingDB PrimarySearch

BDBM13063 4-(5-methyl-3-phenyl-1,2-oxazol-4-yl)benzene-1-sulfonamide::Bextra::CHEMBL865::VLX::Valdecoxib::cid_119607

SMILES: Cc1onc(c1-c1ccc(cc1)S(N)(=O)=O)-c1ccccc1

InChI Key: InChIKey=LNPDTQAFDNKSHK-UHFFFAOYSA-N

Data: 123 KI 31 IC50 8 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 162 hits for monomerid = 13063
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Carbonic anhydrase 1 (Human)	BDBM13063 (CHEMBL865 \| cid_119607 \| Bextra \| VLX \| 4-(5-methy...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	5.40E+4	n/a	n/a	n/a	n/a	7.4	25
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Carbonic anhydrase 2 (Human)	BDBM13063 (CHEMBL865 \| cid_119607 \| Bextra \| VLX \| 4-(5-methy...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	43	n/a	n/a	n/a	n/a	7.4	25
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Carbonic anhydrase 4 (Bovine)	BDBM13063 (CHEMBL865 \| cid_119607 \| Bextra \| VLX \| 4-(5-methy...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	340	n/a	n/a	n/a	n/a	7.4	25
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Carbonic anhydrase 9 (Human)	BDBM13063 (CHEMBL865 \| cid_119607 \| Bextra \| VLX \| 4-(5-methy...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	27	n/a	n/a	n/a	n/a	7.5	20
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Cell division control protein 42 homolog (Human)	BDBM13063 (CHEMBL865 \| cid_119607 \| Bextra \| VLX \| 4-(5-methy...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a
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Cell division control protein 42 homolog (Human)	BDBM13063 (CHEMBL865 \| cid_119607 \| Bextra \| VLX \| 4-(5-methy...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a
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Ras-related protein Rab-7a (Dog)	BDBM13063 (CHEMBL865 \| cid_119607 \| Bextra \| VLX \| 4-(5-methy...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a
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Ras-related protein Rab-2A (Dog)	BDBM13063 (CHEMBL865 \| cid_119607 \| Bextra \| VLX \| 4-(5-methy...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a
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GTPase KRas [1-37] (Human)	BDBM13063 (CHEMBL865 \| cid_119607 \| Bextra \| VLX \| 4-(5-methy...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a
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Ras-related C3 botulinum toxin substrate 1 (Mouse)	BDBM13063 (CHEMBL865 \| cid_119607 \| Bextra \| VLX \| 4-(5-methy...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a
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GTPase KRas [1-37] (Human)	BDBM13063 (CHEMBL865 \| cid_119607 \| Bextra \| VLX \| 4-(5-methy...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a
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Ras-related C3 botulinum toxin substrate 1 (Mouse)	BDBM13063 (CHEMBL865 \| cid_119607 \| Bextra \| VLX \| 4-(5-methy...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 4 (Human)	BDBM13063 (CHEMBL865 \| cid_119607 \| Bextra \| VLX \| 4-(5-methy...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 2 (Human)	BDBM13063 (CHEMBL865 \| cid_119607 \| Bextra \| VLX \| 4-(5-methy...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 3 (Human)	BDBM13063 (CHEMBL865 \| cid_119607 \| Bextra \| VLX \| 4-(5-methy...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Bile salt export pump (Human)	BDBM13063 (CHEMBL865 \| cid_119607 \| Bextra \| VLX \| 4-(5-methy...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin G/H synthase 2 (Human)	BDBM13063 (CHEMBL865 \| cid_119607 \| Bextra \| VLX \| 4-(5-methy...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin G/H synthase 1 (Human)	BDBM13063 (CHEMBL865 \| cid_119607 \| Bextra \| VLX \| 4-(5-methy...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.40E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin G/H synthase 2 (Human)	BDBM13063 (CHEMBL865 \| cid_119607 \| Bextra \| VLX \| 4-(5-methy...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin G/H synthase 2 (Human)	BDBM13063 (CHEMBL865 \| cid_119607 \| Bextra \| VLX \| 4-(5-methy...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin G/H synthase 1 (Human)	BDBM13063 (CHEMBL865 \| cid_119607 \| Bextra \| VLX \| 4-(5-methy...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.40E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin G/H synthase 2 (Human)	BDBM13063 (CHEMBL865 \| cid_119607 \| Bextra \| VLX \| 4-(5-methy...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin G/H synthase 1 (Human)	BDBM13063 (CHEMBL865 \| cid_119607 \| Bextra \| VLX \| 4-(5-methy...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	2.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin G/H synthase 2 (Human)	BDBM13063 (CHEMBL865 \| cid_119607 \| Bextra \| VLX \| 4-(5-methy...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	570	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin G/H synthase 1 (Human)	BDBM13063 (CHEMBL865 \| cid_119607 \| Bextra \| VLX \| 4-(5-methy...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin G/H synthase 2 (Human)	BDBM13063 (CHEMBL865 \| cid_119607 \| Bextra \| VLX \| 4-(5-methy...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	183	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin G/H synthase 2 (Human)	BDBM13063 (CHEMBL865 \| cid_119607 \| Bextra \| VLX \| 4-(5-methy...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin G/H synthase 1 (Sheep)	BDBM13063 (CHEMBL865 \| cid_119607 \| Bextra \| VLX \| 4-(5-methy...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.57E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin G/H synthase 2 (Human)	BDBM13063 (CHEMBL865 \| cid_119607 \| Bextra \| VLX \| 4-(5-methy...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome c oxidase subunit 2 (Human)	BDBM13063 (CHEMBL865 \| cid_119607 \| Bextra \| VLX \| 4-(5-methy...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome c oxidase subunit 1 (Sheep)	BDBM13063 (CHEMBL865 \| cid_119607 \| Bextra \| VLX \| 4-(5-methy...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	9.62E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin G/H synthase 1 (Human)	BDBM13063 (CHEMBL865 \| cid_119607 \| Bextra \| VLX \| 4-(5-methy...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	3.43E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin G/H synthase 2 (Human)	BDBM13063 (CHEMBL865 \| cid_119607 \| Bextra \| VLX \| 4-(5-methy...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	660	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin G/H synthase 1 (Human)	BDBM13063 (CHEMBL865 \| cid_119607 \| Bextra \| VLX \| 4-(5-methy...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin G/H synthase 2 (Human)	BDBM13063 (CHEMBL865 \| cid_119607 \| Bextra \| VLX \| 4-(5-methy...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	183	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 2 (Human)	BDBM13063 (CHEMBL865 \| cid_119607 \| Bextra \| VLX \| 4-(5-methy...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 4 (Bovine)	BDBM13063 (CHEMBL865 \| cid_119607 \| Bextra \| VLX \| 4-(5-methy...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
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Carbonic anhydrase 1 (Human)	BDBM13063 (CHEMBL865 \| cid_119607 \| Bextra \| VLX \| 4-(5-methy...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	5.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin G/H synthase 2 (Human)	BDBM13063 (CHEMBL865 \| cid_119607 \| Bextra \| VLX \| 4-(5-methy...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	5.01	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase (Sulfurihydrogenibium sp. (strain YO3AOP1))	BDBM13063 (CHEMBL865 \| cid_119607 \| Bextra \| VLX \| 4-(5-methy...) Show SMILES Show InChI	GoogleScholar	UniChem	5.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 12 (Human)	BDBM13063 (CHEMBL865 \| cid_119607 \| Bextra \| VLX \| 4-(5-methy...) Show SMILES Show InChI	GoogleScholar	UniChem	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 12 (Human)	BDBM13063 (CHEMBL865 \| cid_119607 \| Bextra \| VLX \| 4-(5-methy...) Show SMILES Show InChI	GoogleScholar	UniChem	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 12 (Human)	BDBM13063 (CHEMBL865 \| cid_119607 \| Bextra \| VLX \| 4-(5-methy...) Show SMILES Show InChI	GoogleScholar	UniChem	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 12 (Human)	BDBM13063 (CHEMBL865 \| cid_119607 \| Bextra \| VLX \| 4-(5-methy...) Show SMILES Show InChI	GoogleScholar	UniChem	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 12 (Human)	BDBM13063 (CHEMBL865 \| cid_119607 \| Bextra \| VLX \| 4-(5-methy...) Show SMILES Show InChI	GoogleScholar	UniChem	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 9 (Human)	BDBM13063 (CHEMBL865 \| cid_119607 \| Bextra \| VLX \| 4-(5-methy...) Show SMILES Show InChI	GoogleScholar	UniChem	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 9 (Human)	BDBM13063 (CHEMBL865 \| cid_119607 \| Bextra \| VLX \| 4-(5-methy...) Show SMILES Show InChI	GoogleScholar	UniChem	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 9 (Human)	BDBM13063 (CHEMBL865 \| cid_119607 \| Bextra \| VLX \| 4-(5-methy...) Show SMILES Show InChI	GoogleScholar	UniChem	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 9 (Human)	BDBM13063 (CHEMBL865 \| cid_119607 \| Bextra \| VLX \| 4-(5-methy...) Show SMILES Show InChI	GoogleScholar	UniChem	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 9 (Human)	BDBM13063 (CHEMBL865 \| cid_119607 \| Bextra \| VLX \| 4-(5-methy...) Show SMILES Show InChI	GoogleScholar	UniChem	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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