BDBM13076 6-chloro-1,1-dioxo-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide::BMCL182567 Compound 6a::Dichlothiazide::Hydro-D::Hydrochlorothiazide::Hypothiazide::JFD00715::Oretic::cid_3639

SMILES: c1c2c(cc(c1Cl)S(=O)(=O)N)S(=O)(=O)NCN2

InChI Key: InChIKey=JZUFKLXOESDKRF-UHFFFAOYSA-N

Data: 61 KI  6 IC50  3 Kd  1 EC50

PDB links: 3 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 71 hits for monomerid = 13076   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 2 (Human)	BDBM13076 (JFD00715 | cid_3639 | 6-chloro-1,1-dioxo-3,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2J2 (Human)	BDBM13076 (JFD00715 | cid_3639 | 6-chloro-1,1-dioxo-3,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 3 (Human)	BDBM13076 (JFD00715 | cid_3639 | 6-chloro-1,1-dioxo-3,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.00E+5	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM13076 (JFD00715 | cid_3639 | 6-chloro-1,1-dioxo-3,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	7.19E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM13076 (JFD00715 | cid_3639 | 6-chloro-1,1-dioxo-3,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	7.4	25
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Bile salt export pump (Human)	BDBM13076 (JFD00715 | cid_3639 | 6-chloro-1,1-dioxo-3,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 2 (Human)	BDBM13076 (JFD00715 | cid_3639 | 6-chloro-1,1-dioxo-3,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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ATP-binding cassette sub-family C member 4 (Human)	BDBM13076 (JFD00715 | cid_3639 | 6-chloro-1,1-dioxo-3,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Heat shock factor protein 1 (Mouse)	BDBM13076 (JFD00715 | cid_3639 | 6-chloro-1,1-dioxo-3,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.95E+5	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 3 (Human)	BDBM13076 (JFD00715 | cid_3639 | 6-chloro-1,1-dioxo-3,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Carbonic anhydrase (Sulfurihydrogenibium sp. (strain YO3AOP1))	BDBM13076 (JFD00715 | cid_3639 | 6-chloro-1,1-dioxo-3,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		7.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase (African malaria mosquito)	BDBM13076 (JFD00715 | cid_3639 | 6-chloro-1,1-dioxo-3,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM13076 (JFD00715 | cid_3639 | 6-chloro-1,1-dioxo-3,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		290	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM13076 (JFD00715 | cid_3639 | 6-chloro-1,1-dioxo-3,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		290	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM13076 (JFD00715 | cid_3639 | 6-chloro-1,1-dioxo-3,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		290	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM13076 (JFD00715 | cid_3639 | 6-chloro-1,1-dioxo-3,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		290	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM13076 (JFD00715 | cid_3639 | 6-chloro-1,1-dioxo-3,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		290	n/a	n/a	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM13076 (JFD00715 | cid_3639 | 6-chloro-1,1-dioxo-3,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		290	n/a	n/a	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM13076 (JFD00715 | cid_3639 | 6-chloro-1,1-dioxo-3,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		290	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM13076 (JFD00715 | cid_3639 | 6-chloro-1,1-dioxo-3,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		290	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM13076 (JFD00715 | cid_3639 | 6-chloro-1,1-dioxo-3,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		290	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM13076 (JFD00715 | cid_3639 | 6-chloro-1,1-dioxo-3,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		290	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM13076 (JFD00715 | cid_3639 | 6-chloro-1,1-dioxo-3,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		290	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM13076 (JFD00715 | cid_3639 | 6-chloro-1,1-dioxo-3,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		290	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM13076 (JFD00715 | cid_3639 | 6-chloro-1,1-dioxo-3,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		290	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM13076 (JFD00715 | cid_3639 | 6-chloro-1,1-dioxo-3,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		290	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM13076 (JFD00715 | cid_3639 | 6-chloro-1,1-dioxo-3,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		290	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM13076 (JFD00715 | cid_3639 | 6-chloro-1,1-dioxo-3,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		290	-8.91	n/a	n/a	n/a	n/a	n/a	7.4	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM13076 (JFD00715 | cid_3639 | 6-chloro-1,1-dioxo-3,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		290	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM13076 (JFD00715 | cid_3639 | 6-chloro-1,1-dioxo-3,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		290	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM13076 (JFD00715 | cid_3639 | 6-chloro-1,1-dioxo-3,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		290	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM13076 (JFD00715 | cid_3639 | 6-chloro-1,1-dioxo-3,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		290	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM13076 (JFD00715 | cid_3639 | 6-chloro-1,1-dioxo-3,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		290	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM13076 (JFD00715 | cid_3639 | 6-chloro-1,1-dioxo-3,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		290	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM13076 (JFD00715 | cid_3639 | 6-chloro-1,1-dioxo-3,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		290	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Carbonic anhydrase, alpha family (Thiomicrospira crunogena (strain XCL-2))	BDBM13076 (JFD00715 | cid_3639 | 6-chloro-1,1-dioxo-3,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		296	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Human)	BDBM13076 (JFD00715 | cid_3639 | 6-chloro-1,1-dioxo-3,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		328	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Human)	BDBM13076 (JFD00715 | cid_3639 | 6-chloro-1,1-dioxo-3,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		328	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Human)	BDBM13076 (JFD00715 | cid_3639 | 6-chloro-1,1-dioxo-3,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		328	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Human)	BDBM13076 (JFD00715 | cid_3639 | 6-chloro-1,1-dioxo-3,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		328	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Human)	BDBM13076 (JFD00715 | cid_3639 | 6-chloro-1,1-dioxo-3,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		328	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Human)	BDBM13076 (JFD00715 | cid_3639 | 6-chloro-1,1-dioxo-3,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		328	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Human)	BDBM13076 (JFD00715 | cid_3639 | 6-chloro-1,1-dioxo-3,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		328	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Human)	BDBM13076 (JFD00715 | cid_3639 | 6-chloro-1,1-dioxo-3,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		328	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Human)	BDBM13076 (JFD00715 | cid_3639 | 6-chloro-1,1-dioxo-3,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		328	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Human)	BDBM13076 (JFD00715 | cid_3639 | 6-chloro-1,1-dioxo-3,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		328	n/a	n/a	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Human)	BDBM13076 (JFD00715 | cid_3639 | 6-chloro-1,1-dioxo-3,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		328	-8.84	n/a	n/a	n/a	n/a	n/a	7.4	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Human)	BDBM13076 (JFD00715 | cid_3639 | 6-chloro-1,1-dioxo-3,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		328	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Human)	BDBM13076 (JFD00715 | cid_3639 | 6-chloro-1,1-dioxo-3,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		328	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Human)	BDBM13076 (JFD00715 | cid_3639 | 6-chloro-1,1-dioxo-3,4-dihyd...) Show SMILES Show InChI	GoogleScholar	UniChem		328	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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