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BDBM130871 US8829199, 139

SMILES: Cc1nc2ccc(cc2n1)-n1ncc(C(=O)c2cc3c(NCCc4ccncc4)cccc3[nH]2)c1N

InChI Key:

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 130871   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fibroblast growth factor receptor 1


(Homo sapiens (Human))
BDBM130871
PNG
(US8829199, 139)
Show SMILES Cc1nc2ccc(cc2n1)-n1ncc(C(=O)c2cc3c(NCCc4ccncc4)cccc3[nH]2)c1N
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 8.5n/an/an/an/an/an/a



Chugai Seiyaku Kabushiki Kaisha

US Patent


Assay Description
The FGFR1-inhibiting activity was measured based on the activity to inhibit phosphorylation of the biotinylated peptide EGPWLEEEEEAYGWMDF by the huma...


US Patent US8829199 (2014)


BindingDB Entry DOI: 10.7270/Q26T0KB8
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM130871
PNG
(US8829199, 139)
Show SMILES Cc1nc2ccc(cc2n1)-n1ncc(C(=O)c2cc3c(NCCc4ccncc4)cccc3[nH]2)c1N
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 18n/an/an/an/an/an/a



Chugai Seiyaku Kabushiki Kaisha

US Patent


Assay Description
The FGFR3-inhibiting activity was measured based on the activity to inhibit phosphorylation of the biotinylated peptide EGPWLEEEEEAYGWMDF by the huma...


US Patent US8829199 (2014)


BindingDB Entry DOI: 10.7270/Q26T0KB8
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 2


(Homo sapiens (Human))
BDBM130871
PNG
(US8829199, 139)
Show SMILES Cc1nc2ccc(cc2n1)-n1ncc(C(=O)c2cc3c(NCCc4ccncc4)cccc3[nH]2)c1N
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 29n/an/an/an/an/an/a



Chugai Seiyaku Kabushiki Kaisha

US Patent


Assay Description
The FGFR2-inhibiting activity was measured based on the activity to inhibit phosphorylation of the biotinylated peptide EGPWLEEEEEAYGWMDF by the huma...


US Patent US8829199 (2014)


BindingDB Entry DOI: 10.7270/Q26T0KB8
More data for this
Ligand-Target Pair