BDBM130909 US10683289, Example Staurosporine::US10927120, Compound staurosporine::US8822500, Stauro- sporine::US9920060, Staurosporine

SMILES: C[C@@]12[C@@H]([C@@H](C[C@@H](O1)n3c4ccccc4c5c3c6n2c7ccccc7c6c8c5C(=O)NC8)NC)OC

InChI Key: InChIKey=HKSZLNNOFSGOKW-UHFFFAOYSA-N

Data: 13 IC50

PDB links: 89 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 387 hits for monomerid = 130909   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor tyrosine-protein kinase erbB-2 (Human)	BDBM130909 (US8822500, Stauro- sporine | US9920060, Staurospor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	63	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Serine/threonine-protein kinase receptor R3 (Human)	BDBM130909 (US8822500, Stauro- sporine | US9920060, Staurospor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.36	n/a	n/a	n/a	n/a	7.5	n/a
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Insulin-like growth factor 1 receptor (Human)	BDBM130909 (US8822500, Stauro- sporine | US9920060, Staurospor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	71.5	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
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Insulin receptor (Human)	BDBM130909 (US8822500, Stauro- sporine | US9920060, Staurospor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	36.4	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
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High affinity nerve growth factor receptor (Human)	BDBM130909 (US8822500, Stauro- sporine | US9920060, Staurospor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.41	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
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BDNF/NT-3 growth factors receptor (Human)	BDBM130909 (US8822500, Stauro- sporine | US9920060, Staurospor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.18	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
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NT-3 growth factor receptor (Human)	BDBM130909 (US8822500, Stauro- sporine | US9920060, Staurospor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.525	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
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Proto-oncogene tyrosine-protein kinase ROS (Human)	BDBM130909 (US8822500, Stauro- sporine | US9920060, Staurospor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.248	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
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Proto-oncogene tyrosine-protein kinase receptor Ret (Human)	BDBM130909 (US8822500, Stauro- sporine | US9920060, Staurospor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.19	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
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Hepatocyte growth factor receptor (Human)	BDBM130909 (US8822500, Stauro- sporine | US9920060, Staurospor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	107	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
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Mitogen-activated protein kinase kinase kinase 5 (Human)	BDBM130909 (US8822500, Stauro- sporine | US9920060, Staurospor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Human)	BDBM130909 (US8822500, Stauro- sporine | US9920060, Staurospor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.93	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Cyclin-dependent kinase 4/G1/S-specific cyclin-D1 [L188C] (Human)	BDBM130909 (US8822500, Stauro- sporine | US9920060, Staurospor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	37.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Human)	BDBM130909 (US8822500, Stauro- sporine | US9920060, Staurospor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Human)	BDBM130909 (US8822500, Stauro- sporine | US9920060, Staurospor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Activated CDC42 kinase 1 (Human)	BDBM130909 (US8822500, Stauro- sporine | US9920060, Staurospor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Human)	BDBM130909 (US8822500, Stauro- sporine | US9920060, Staurospor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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RAC-beta serine/threonine-protein kinase (Human)	BDBM130909 (US8822500, Stauro- sporine | US9920060, Staurospor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
RAC-gamma serine/threonine-protein kinase (Human)	BDBM130909 (US8822500, Stauro- sporine | US9920060, Staurospor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Tyrosine-protein kinase receptor UFO (Human)	BDBM130909 (US8822500, Stauro- sporine | US9920060, Staurospor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Tyrosine-protein kinase BTK (Human)	BDBM130909 (US8822500, Stauro- sporine | US9920060, Staurospor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk1 (Human)	BDBM130909 (US8822500, Stauro- sporine | US9920060, Staurospor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Mitogen-activated protein kinase kinase kinase 8 (Human)	BDBM130909 (US8822500, Stauro- sporine | US9920060, Staurospor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Receptor tyrosine-protein kinase erbB-2 (Human)	BDBM130909 (US8822500, Stauro- sporine | US9920060, Staurospor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	73	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 3 (Human)	BDBM130909 (US8822500, Stauro- sporine | US9920060, Staurospor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.73E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 alpha (Human)	BDBM130909 (US8822500, Stauro- sporine | US9920060, Staurospor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Insulin-like growth factor 1 receptor (Human)	BDBM130909 (US8822500, Stauro- sporine | US9920060, Staurospor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Inhibitor of nuclear factor kappa-B kinase subunit alpha (Human)	BDBM130909 (US8822500, Stauro- sporine | US9920060, Staurospor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	77	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Insulin receptor (Human)	BDBM130909 (US8822500, Stauro- sporine | US9920060, Staurospor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Tyrosine-protein kinase JAK2 (Human)	BDBM130909 (US8822500, Stauro- sporine | US9920060, Staurospor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Vascular endothelial growth factor receptor 2 (Human)	BDBM130909 (US8822500, Stauro- sporine | US9920060, Staurospor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Tyrosine-protein kinase Lck (Human)	BDBM130909 (US8822500, Stauro- sporine | US9920060, Staurospor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Tyrosine-protein kinase Lyn (Human)	BDBM130909 (US8822500, Stauro- sporine | US9920060, Staurospor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha (Human)	BDBM130909 (US8822500, Stauro- sporine | US9920060, Staurospor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Human)	BDBM130909 (US8822500, Stauro- sporine | US9920060, Staurospor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Sgk1 (Human)	BDBM130909 (US8822500, Stauro- sporine | US9920060, Staurospor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Tyrosine-protein kinase receptor TYRO3 (Human)	BDBM130909 (US8822500, Stauro- sporine | US9920060, Staurospor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Wee1-like protein kinase (Human)	BDBM130909 (US8822500, Stauro- sporine | US9920060, Staurospor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase N1 (Human)	BDBM130909 (US8822500, Stauro- sporine | US9920060, Staurospor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Dual specificity protein kinase TTK (Human)	BDBM130909 (US8822500, Stauro- sporine | US9920060, Staurospor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity protein kinase TTK (Human)	BDBM130909 (US8822500, Stauro- sporine | US9920060, Staurospor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity protein kinase TTK (Human)	BDBM130909 (US8822500, Stauro- sporine | US9920060, Staurospor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	149	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity protein kinase TTK (Human)	BDBM130909 (US8822500, Stauro- sporine | US9920060, Staurospor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	606	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 alpha (Human)	BDBM130909 (US8822500, Stauro- sporine | US9920060, Staurospor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase kinase 4 (Human)	BDBM130909 (US8822500, Stauro- sporine | US9920060, Staurospor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL2 (Human)	BDBM130909 (US8822500, Stauro- sporine | US9920060, Staurospor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type IV (Human)	BDBM130909 (US8822500, Stauro- sporine | US9920060, Staurospor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Mouse)	BDBM130909 (US8822500, Stauro- sporine | US9920060, Staurospor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Mouse)	BDBM130909 (US8822500, Stauro- sporine | US9920060, Staurospor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Mouse)	BDBM130909 (US8822500, Stauro- sporine | US9920060, Staurospor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair