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BDBM131167 US8835472, 2.100

SMILES: CC(Cc1ccc(cc1)C#Cc1ccc(OC2CC2)cc1)NC(C)=O

InChI Key: InChIKey=ZOSQRGITCYTZOS-UHFFFAOYNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 131167   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Acetyl-CoA carboxylase 2 (ACC2)


(Homo sapiens (Human))
BDBM131167
PNG
(US8835472, 2.100)
Show SMILES CC(Cc1ccc(cc1)C#Cc1ccc(OC2CC2)cc1)NC(C)=O
Show InChI InChI=1/C22H23NO2/c1-16(23-17(2)24)15-20-7-5-18(6-8-20)3-4-19-9-11-21(12-10-19)25-22-13-14-22/h5-12,16,22H,13-15H2,1-2H3,(H,23,24)
PDB
MMDB

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PC sid
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Similars

US Patent
n/an/a 120n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Malonyl CoA formation by acetyl CoA carboxylases is stoichometrically linked to the consumption of ATP. ACC2 activity is measured in a NADH-linked ki...


US Patent US8835472 (2014)


BindingDB Entry DOI: 10.7270/Q25T3J6W
More data for this
Ligand-Target Pair