BDBM1312 3-Aminopyridin-2(1H)-one analogue 32::5-ethyl-6-methyl-3-{[(7-methyl-1,3-benzoxazol-2-yl)methyl]amino}-1,2-dihydropyridin-2-one::Pyridinone deriv. 12

SMILES CCc1cc(NCc2nc3cccc(C)c3o2)c(=O)[nH]c1C

InChI Key InChIKey=HASDKQMKEXOVJW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 1312   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Sharp And Dohme Research Laboratories

LigandPNGBDBM1312(3-Aminopyridin-2(1H)-one analogue 32 | 5-ethyl-6-m...)
Affinity DataIC50:  55nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Sharp And Dohme Research Laboratories

LigandPNGBDBM1312(3-Aminopyridin-2(1H)-one analogue 32 | 5-ethyl-6-m...)
Affinity DataIC50:  55nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed