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BDBM13181 (2S)-2-amino-N-(5,7-dimethyl-1,8-naphthyridin-2-yl)propanamide::SMAC mimetic compound 8

SMILES: C[C@H](N)C(=O)Nc1ccc2c(C)cc(C)nc2n1

InChI Key: InChIKey=NEVIWLQURZYMJU-IMWMWJONNA-N

Data: 1 Kd

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 13181   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
XIAP-BIR3


(Homo sapiens (Human))
BDBM13181
PNG
((2S)-2-amino-N-(5,7-dimethyl-1,8-naphthyridin-2-yl...)
Show SMILES C[C@H](N)C(=O)Nc1ccc2c(C)cc(C)nc2n1
Show InChI InChI=1/C13H16N4O/c1-7-6-8(2)15-12-10(7)4-5-11(16-12)17-13(18)9(3)14/h4-6,9H,14H2,1-3H3,(H,15,16,17,18)/t9-/s2
PDB
MMDB

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Similars

Article
PubMed
n/an/an/a 2.00E+4n/an/an/a7.422



Abbott Laboratories



Assay Description
A fluorescence polarization anisotropy (FPA) competition assay was used to determine the affinities of compounds to BIR3 protein. Fluorescence polari...


Bioorg Med Chem Lett 15: 771-5 (2005)


Article DOI: 10.1016/j.bmcl.2004.11.010
BindingDB Entry DOI: 10.7270/Q23T9FFF
More data for this
Ligand-Target Pair