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BDBM132131 USRE45173, 56A

SMILES: COc1cccc(c1)N1CCN(C1=O)c1cnccc1C

InChI Key: InChIKey=RVXWPFRBHJOZMW-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 132131   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cytochrome P450 17A1


(Homo sapiens (Human))
BDBM132131
PNG
(USRE45173, 56A)
Show SMILES COc1cccc(c1)N1CCN(C1=O)c1cnccc1C
Show InChI InChI=1S/C16H17N3O2/c1-12-6-7-17-11-15(12)19-9-8-18(16(19)20)13-4-3-5-14(10-13)21-2/h3-7,10-11H,8-9H2,1-2H3
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Similars

US Patent
n/an/a 25n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
Cytochrome P450, 17-20 lyase (CYP17-lyase) assay development using recombinant human CYP17 enzyme and 17-alpha -hydroxy pregnenolone [21-3H] as the s...


US Patent USRE45173 (2014)


BindingDB Entry DOI: 10.7270/Q2MW2FT2
More data for this
Ligand-Target Pair