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BDBM132145 USRE45173, 84A

SMILES: Clc1ccncc1N1CCN(C1=O)c1ccc2ncsc2c1

InChI Key: InChIKey=MNQWCUSURHKAFL-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 132145   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cytochrome P450 17A1


(Homo sapiens (Human))
BDBM132145
PNG
(USRE45173, 84A)
Show SMILES Clc1ccncc1N1CCN(C1=O)c1ccc2ncsc2c1
Show InChI InChI=1S/C15H11ClN4OS/c16-11-3-4-17-8-13(11)20-6-5-19(15(20)21)10-1-2-12-14(7-10)22-9-18-12/h1-4,7-9H,5-6H2
PDB

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Similars

US Patent
n/an/a 85n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
Cytochrome P450, 17-20 lyase (CYP17-lyase) assay development using recombinant human CYP17 enzyme and 17-alpha -hydroxy pregnenolone [21-3H] as the s...


US Patent USRE45173 (2014)


BindingDB Entry DOI: 10.7270/Q2MW2FT2
More data for this
Ligand-Target Pair